Background: Alzheimer's Disease (AD) tends to co-exists with other pathologies, with vascular pathology being the most common type. It is well known that the presence of comorbidities results in differential disease trajectories and heterogeneity in clinical phenotypes. The aim of ...

Background: Sexual minorities (i.e. people who identify as non-heterosexual) show several health disparities. However, risk/protective factors relevant to cognitive health of sexual minority older adults (SMOAs) have not been fully investigated. The aim of this study was to quantify t...

Background: Sporadic Alzheimer's disease (AD) accounts for >90% of AD cases, of which 70% are thought to be due to a combination of several risk genes. Investigating polygenic risk scores (PRS) that examine many genes simultaneously may increase understanding of gene-gene ...

Background: Acetylcholinesterase inhibitors are used to delay cognitive decline due to Alzheimer's disease (AD) by preventing breakdown of acetylcholine. Such treatment appears to be associated with cerebral changes, although the mechanism of action has not been clarified yet. This stu...

A measurement of event-shape variables is presented, using a data sample produced in a special run with approximately one inelastic proton-proton collision per bunch crossing. The data were collected with the CMS detector at a center-of-mass energy of 13 TeV, corresponding to an integra...

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Introduction: There is an ongoing debate about the neural mechanisms and subjective preferences involved in the processing of social rewards compared to non-social reward types. Methods: Using whole-brain functional magnetic resonance imaging (fMRI), we examined brain activa...

This paper introduces a new efficient hyperbolic high-order shear deformation theory (HHSDT) with a shape parameter (<i>Sₚ</i>) to study the vibration response of porous functionally graded material (FGM) plates and nanoplates. The shape parameter is optimized using a simple algorithm...