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http://bura.brunel.ac.uk/handle/2438/22103| Title: | Perspectives on ENCODE |
| Authors: | Snyder, MP Gingeras, TR Abascal, F Acosta, R Addleman, NJ Adrian, J Afzal, V Aken, B Akiyama, JA Jammal, OA Amrhein, H Dileep, V Ding, B Djebali, S Dobin, A Dominguez, D Sisu, C Donaldson, S Drenkow, J Dreszer, TR Drier, Y Duff, MO Dunn, D Anderson, SM Andrews, GR Eastman, C Ecker, JR Edwards, MD El-Ali, N Elhajjajy, SI Antoshechkin, I Ardlie, KG Armstrong, J Astley, M Banerjee, B Barkal, AA Barnes, IHA Barozzi, I Barrell, D Barson, G Bates, D Baymuradov, UK Bazile, C Beer, MA Beik, S Bender, MA Bennett, R Bouvrette, LPB Bernstein, BE Berry, A Bhaskar, A Bignell, A Blue, SM Bodine, DM Boix, C Boley, N Borrman, T Borsari, B Boyle, AP Brandsmeier, LA Breschi, A Bresnick, EH Brooks, JA Buckley, M Burge, CB Byron, R Cahill, E Cai, L Cao, L Carty, M Castanon, RG Castillo, A Chaib, H Chan, ET Chee, DR Chee, S Chen, H Chen, H Chen, JY Chen, S Cherry, JM Chhetri, SB Choudhary, JS Chrast, J Chung, D Clarke, D Cody, NAL Coppola, CJ Coursen, J D’Ippolito, AM Dalton, S Danyko, C Davidson, C Davila-Velderrain, J Davis, CA Dekker, J Deran, A DeSalvo, G Despacio-Reyes, G Dewey, CN Dickel, DE Diegel, M Diekhans, M |
| Keywords: | epigenetic;epigenomics;genome;transcriptomics |
| Issue Date: | 30-Jul-2020 |
| Publisher: | Springer Nature |
| Citation: | The ENCODE Project Consortium, Snyder, M.P., Gingeras, T.R. et al. (2020) 'Perspectives on ENCODE', Nature, 2020, 583 (7818), pp. 693 - 698. doi:10.1038/s41586-020-2449-8. |
| Abstract: | © 2020, The Author(s). The Encylopedia of DNA Elements (ENCODE) Project launched in 2003 with the long-term goal of developing a comprehensive map of functional elements in the human genome. These included genes, biochemical regions associated with gene regulation (for example, transcription factor binding sites, open chromatin, and histone marks) and transcript isoforms. The marks serve as sites for candidate cis-regulatory elements (cCREs) that may serve functional roles in regulating gene expression1. The project has been extended to model organisms, particularly the mouse. In the third phase of ENCODE, nearly a million and more than 300,000 cCRE annotations have been generated for human and mouse, respectively, and these have provided a valuable resource for the scientific community. |
| Description: | Supplementary information is available for this paper at https://doi.org/10.1038/s41586-020- 2449-8. Correction to: Nature https://doi.org/10.1038/s41586-020-2449-8published online 29 July 2020. In this Article, the authors Rizi Ai (Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, USA) and Shantao Li (Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA) were mistakenly omitted from the ENCODE Project Consortium author list. The original Article has been corrected online. Author Correction: Perspectives on ENCODE (published 22 April 2022: The ENCODE Project Consortium., Snyder, M.P., Gingeras, T.R. et al. (2022) 'Author Correction: Perspectives on ENCODE', Nature, 605, E4. doi: 10.1038/s41586-021-04213-8). Correction to: Nature https://doi.org/10.1038/s41586-020-2449-8published online 29 July 2020. In this Article, the authors Rizi Ai (Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, USA) and Shantao Li (Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA) were mistakenly omitted from the ENCODE Project Consortium author list. The original Article has been corrected online. |
| URI: | https://bura.brunel.ac.uk/handle/2438/22103 |
| DOI: | https://doi.org/10.1038/s41586-020-2449-8 |
| ISSN: | 0028-0836 |
| Appears in Collections: | Dept of Life Sciences Research Papers |
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