Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/22103
Title: Perspectives on ENCODE
Authors: Abascal, F
Acosta, R
Addleman, NJ
Adrian, J
Afzal, V
Aken, B
Akiyama, JA
Jammal, OA
Amrhein, H
Anderson, SM
Andrews, GR
Antoshechkin, I
Ardlie, KG
Armstrong, J
Astley, M
Banerjee, B
Barkal, AA
Barnes, IHA
Barozzi, I
Barrell, D
Barson, G
Bates, D
Baymuradov, UK
Bazile, C
Beer, MA
Beik, S
Bender, MA
Bennett, R
Bouvrette, LPB
Bernstein, BE
Berry, A
Bhaskar, A
Bignell, A
Blue, SM
Bodine, DM
Boix, C
Boley, N
Borrman, T
Borsari, B
Boyle, AP
Brandsmeier, LA
Breschi, A
Bresnick, EH
Brooks, JA
Buckley, M
Burge, CB
Byron, R
Cahill, E
Cai, L
Cao, L
Carty, M
Castanon, RG
Castillo, A
Chaib, H
Chan, ET
Chee, DR
Chee, S
Chen, H
Chen, H
Chen, JY
Chen, S
Cherry, JM
Chhetri, SB
Choudhary, JS
Chrast, J
Chung, D
Clarke, D
Cody, NAL
Coppola, CJ
Coursen, J
D’Ippolito, AM
Dalton, S
Danyko, C
Davidson, C
Davila-Velderrain, J
Davis, CA
Dekker, J
Deran, A
DeSalvo, G
Despacio-Reyes, G
Dewey, CN
Dickel, DE
Diegel, M
Diekhans, M
Dileep, V
Ding, B
Djebali, S
Dobin, A
Dominguez, D
Donaldson, S
Drenkow, J
Dreszer, TR
Drier, Y
Duff, MO
Dunn, D
Eastman, C
Ecker, JR
Edwards, MD
El-Ali, N
Elhajjajy, SI
Keywords: epigenetic;epigenomics;genome;transcriptomics
Issue Date: 2020
Publisher: Springer Nature
Citation: The ENCODE Project Consortium, Snyder, M.P. et al. (2020) 'Perspectives on ENCODE', Nature, 2020, 583 (7818), pp. 693 - 698. doi:10.1038/s41586-020-2449-8.
Abstract: © 2020, The Author(s). The Encylopedia of DNA Elements (ENCODE) Project launched in 2003 with the long-term goal of developing a comprehensive map of functional elements in the human genome. These included genes, biochemical regions associated with gene regulation (for example, transcription factor binding sites, open chromatin, and histone marks) and transcript isoforms. The marks serve as sites for candidate cis-regulatory elements (cCREs) that may serve functional roles in regulating gene expression1. The project has been extended to model organisms, particularly the mouse. In the third phase of ENCODE, nearly a million and more than 300,000 cCRE annotations have been generated for human and mouse, respectively, and these have provided a valuable resource for the scientific community.
Description: Supplementary information is available for this paper at https://doi.org/10.1038/s41586-020- 2449-8.
URI: https://bura.brunel.ac.uk/handle/2438/22103
DOI: https://doi.org/10.1038/s41586-020-2449-8
ISSN: 0028-0836
Appears in Collections:Dept of Life Sciences Research Papers

Files in This Item:
File Description SizeFormat 
FullText.pdf1.75 MBAdobe PDFView/Open


This item is licensed under a Creative Commons License Creative Commons