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|Title: ||Is phosphodiesterase type 5 inhibitor use associated with condom breakage?|
|Authors: ||Crosby, RA|
|Publication Date: ||2009|
|Publisher: ||BMJ Publishing Group|
|Citation: ||Sexually Transmitted Infections 85(5): 404-405, Sep 2009|
|Abstract: ||We tested the hypothesis that phosphodiesterase type 5 inhibitor (PDE5i) use would be associated with increased
likelihood of condom breakage using an event-specific analysis.
A convenience sample of 440 men completed an internetbased questionnaire that assessed variables pertaining to the last time they used condoms for penile-vaginal intercourse (PVI). A bivariate (screening) analysis was
performed to identify covariates for a multivariate analysis using logistic regression.
Altogether, 5.9% of the men reported breakage and 9.5% reported PDE5i use during the last time a condom was used for PVI. Among men who had used PDE5i during the
last condom-protected occasion of PVI, 11.9% reported breakage compared with 5.3% of those not reporting PDE5i use. Adjusting for men’s age, ethnic minority status, marital status, reported duration of PVI and alcohol
use at last PVI, those using PDE5i were about four times more likely to also report condom breakage (AOR 4.02; 95% CI 1.20 to 13.48; p=0.04). Of note, duration of PVI
was independently associated with breakage (AOR 1.36; CI 1.02 to 1.83; p=0.04).
Findings suggest that PDE5i use may potentially be associated with increased odds of condom breakage among some men.|
|Description: ||This is an open access article - Copyright © 2009 by the BMJ Publishing Group Ltd. All rights reserved.|
|Sponsorship: ||Support for this project was provided, in part, by the Rural Center for AIDS/
STD Prevention, a joint project of Indiana University, University of Colorado and the
University of Kentucky, and by The Kinsey Institute, Indiana University.|
|Appears in Collections:||School of Social Sciences Research Papers|
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