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Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/5617

Title: Toroidal coil chromatography: The effect of scale-up and "g" field on stage efficiency
Authors: Sutherland, IA
Hewitson, P
De Folter, J
Keywords: Process scale
Toroidal coil chromatography
TCC
Publication Date: 2010
Publisher: Springer BV
Citation: Journal of Chromatography A, 1218(36): 6144–6147, Dec 2010
Abstract: Selected test results have been taken from various publications and resolution and stage efficiency measured using an established model. All experiments used the same sample and, where possible, the same sample loading. The results show that stage mixing efficiencies have increased from 1.1% in 1998 to greater than 25% in the latest scaled-up version of a Toroidal coil chromatography (TCC) instrument working at 240g.
Description: This work was supported by the UK BBSRC (Follow-on Grant No. BB/FOF/206) following on from the BBSRC protein purification study (DEMPRO-Grant No. BB/C506364/1). This article is available from the specified link - Copyright @ 2010 Springer BV
Sponsorship: This article has been made available through the Brunel Open Access Publishing Fund
URI: http://www.sciencedirect.com/science/article/pii/S0021967310018017
http://bura.brunel.ac.uk/handle/2438/5617
DOI: http://dx.doi.org/10.1016/j.chroma.2010.12.090
ISSN: 1873-3778
Appears in Collections:Brunel Institute for Bioengineering (BIB)
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