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Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/6945

Title: Bubbly cavitating flow generation and investigation of its erosional nature for biomedical applications
Authors: Kosar, A
Akbas, A
Sahin, O
Kubilay, A
Oral, O
Gozuacik, D
2nd Micro and Nano Flows Conference (MNF2009)
Keywords: Hydrodynamic cavitation
Bubbly cavitating flow
Microchannel
Cavitation damage
Biomedical treatment
Cancer cells
Publication Date: 2009
Publisher: Brunel University
Citation: 2nd Micro and Nano Flows Conference, Brunel University, West London, UK, 01-02 September 2009
Abstract: The paper presents a study of the generation of hydrodynamic bubbly cavitation in microchannels to investigate the destructive energy output resulting from this phenomenon and its potential use in biomedical applications. The research performed in this study includes the experimental results from bubbly cavitation experiments and the findings showing the destructive effects of bubbly cavitating flow on selected specimens and cells. The bubbles caused by hydrodynamic cavitation are highly destructive at the surfaces of the target medium on which they are carefully focused. The resulting destructive energy output could be effectively used for good means such as destroying kidney stones or killing infected cancer cells. Motivated by this potential, the cavitation damage (material removal) to cancerous cells and chalk pieces having similar material properties as calcium phosphate in human bones was investigated. Also the potential of hydrodynamic bubbly cavitation generated at the microscale for biomedical treatments was revealed using the microchannel configuration of a microorifice (with an inner diameter of 0.147 mm and a length of 1.52cm).
Description: This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the Italian Union of Thermofluid dynamics, the Process Intensification Network, HEXAG - the Heat Exchange Action Group and the Institute of Mathematics and its Applications.
Sponsorship: This work was supported by Sabanc─▒ University Internal Grant for Research Program under Grant FRG-C47004.
URI: http://bura.brunel.ac.uk/handle/2438/6945
ISBN: 978-1-902316-72-7
978-1-902316-73-4
Appears in Collections:Brunel Institute for Bioengineering (BIB)
The Brunel Collection

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