Browsing by Author Themis, M

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Issue DateTitleAuthor(s)
14-Dec-2022Development of a human-based platform to assess adeno-associated viral vector genotoxicityPerera, MS; Suleman, S; Al Haque, S; Zahn, M; Payne, A; Fawaz, S; Khalifa, M; Jobling, S; Hay, D; Franco, M; Fronza, R; Wang, W; Strobel-Freidekind, O; Deichmann, A; Takeuchi, Y; Waddington, SN; Gil-Farina, I; Schmidt, M; Alexander, I; Themis, M
2021Development of a novel in vitro 3D model to identify cancer genes via insertional mutagenesisAlhaque, Sharmin
2016Development of a viral and a non-viral based gene transfer systems using the yeast Saccharomyces cerevisiaeBowden, Jonathan Kirk
2009Differentiation of human fetal mesenchymal stem cells into cells with an oligodendrocyte phenotypeKennea, NL; Waddington, SN; Chan, J; O'Donoghue, K; Yeung, D; Taylor, DL; Al-Allaf, FA; Pirianov, G; Themis, M; Edwards, AD; Fisk, NM; Mehmet, H
2013The fetal mouse is a sensitive genotoxicity model that exposes lentiviral-associated mutagenesis resulting in liver oncogenesisNowrouzi, A; Cheung, WT; Li, T; Zhang, X; Arens, A; Paruzynski, A; Waddington, SN; Osejindu, E; Reja, S; von Kalle, C; Wang, Y; Al-Allaf, F; Gregory, L; Themis, M; Holder, M; Dighe, N; Ruthe, A; Buckley, SM; Bigger, B; Montini, E; Thrasher, AJ; Andrews, R; Roberts, TP; Newbold, RF; Coutelle, C; Schmidt, M; Themis, M
2016Genome wide classification and characterisation of CpG sites in cancer and normal cellsGhorbani, M; Payne, A; Themis, M
5-May-2022HIV- 1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survivalSuleman, S; Payne, A; Bowden, J; Al Haque, S; Zahn, M; Fawaz, S; Khalifa, M; Jobling, S; Hay, D; Franco, M; Fronza, R; Wang, W; Strobel-Freidekind, O; Deichmann, A; Takeuchi, Y; Waddington, SN; Gil-Farina, I; Schmidt, M; Themis, M
25-Nov-2022HIV-1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survivalSuleman, S; Payne, A; Bowden, J; Al Haque, S; Zhan, M; Fawaz, S; Khalifa, MS; Jobling, S; Hay, D; Franco, M; Fronza, R; Wang, W; Strobel-Freidekind, O; Deichmann, A; Takeuchi, Y; Waddington, SN; Gil-Farina, I; Schmidtt, M; Themis, M
2008Intra-amniotic delivery of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred CFTR-knockout miceBuckley, SMK; Waddington, SN; Jezzard, S; Bergau, A; Themis, M; MacVinish, LJ; Cuthbert, AW; Colledge, WH; Coutelle, C
2017Investigating the role of FXN antisense transcript 1 in Friedreich ataxiaMikaeili, Hajar
2023An investigation into the impact of early development and manufacturing processes on cell product qualityKay, Charlotte
2011Investigation of the effects of virus integration on host gene expression in mouse tumour samplesOsejindu, Emma
2023An investigation on the relationship between DNA double strand breaks in the mammalian genome and gene therapy retrovirus vector genotoxicityBhatti, Ataun Nasr
2021An investigation to optimise viral vector production and to generate an in vitro model for genotoxicity assessmentSuleman, Saqlain Mehboob Amanullah
2010LDLR-Gene therapy for familial hypercholesterolaemia: Problems, progress, and perspectivesAl-Allaf, FA; Coutelle, C; Waddington, SN; David, A; Harbottle, R; Themis, M
7-Aug-2018Lentivector Producer Cell Lines with Stably Expressed Vesiculovirus EnvelopesTijani, M; Munis, AM; Perry, C; Sanber, K; Ferraresso, M; Mukhopadhyay, T; Themis, M; Nisoli, I; Mattiuzzo, G; Collins, MK; Takeuchi, Y
1-Oct-2021Lentivirus tethering to the genome is associated with transcription factor binding sites that favour virus survivalSuleman, S; Payne, A; Bowden, J; Al Haque, S; Zhan, M; Fawaz, S; Khalifa, M; Franco, M; Fronza, R; Wang, W; Strobel-Freidekind, O; Diechmann, A; Takeuchi, Y; Waddington, S; Gil-Farina, I; Schmidt, M; Themis, M
2015Lentivirus-meditated frataxin gene delivery reverses genome instability in Friedreich ataxia patient and mouse model fibroblastsKhonsari, Hassan
15-Aug-2016Lentivirus-meditated frataxin gene delivery reverses genome instability in Friedreich ataxia patient and mouse model fibroblastsKhonsari, H; Schneider, M; Al-Mahdawi, S; Chianea, YG; Themis, M; Parris, C; Pook, MA; Themis, M
22-Nov-2018Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector: Construction of optimised cassette for gene therapy of familial hypercholesterolemiaAl-Allaf, FA; Abduljaleel, Z; Athar, M; Taher, MM; Khan, W; Mehmet, H; Colakogullari, M; Apostolidou, S; Bigger, B; Waddington, S; Coutelle, C; Themis, M; Al-Ahdal, MN; Al-Mohanna, FA; Al-Hassnan, ZN; Bouazzaoui, A