Browsing by Author Domingues, AF
Showing results 1 to 9 of 9
Issue Date | Title | Author(s) |
---|---|---|
18-Oct-2016 | A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia | Tzelepis, K; Koike-Yusa, H; De Braekeleer, E; Li, Y; Metzakopian, E; Dovey, OM; Mupo, A; Grinkevich, V; Li, M; Mazan, M; Gozdecka, M; Ohnishi, S; Cooper, J; Patel, M; McKerrell, T; Chen, B; Domingues, AF; Gallipoli, P; Teichmann, S; Ponstingl, H; McDermott, U; Saez-Rodriguez, J; Huntly, BJP; Iorio, F; Pina, C; Vassiliou, GS; Yusa, K |
15-Nov-2022 | Haemogenic Gastruloids Recapitulate Developmental Haematopoiesis and Provide an Ontogeny-Relevant Context to Dissect the Origins of Infant Leukemia | Ragusa, D; Suen, C-W; Torregrosa, G; Dijkhuis, L; Byrne, C; Balayo, T; Tavosanis, A; Durko, J; Place, K; Domingues, AF; Kranc, K; Garcia-Ojalvo, J; Martinez Arias, A; Pina, C |
17-Oct-2018 | Histone Acetyltransferase KAT2A Stabilizes Pluripotency with Control of Transcriptional Heterogeneity | Moris, N; Edri, S; Seyres, D; Kulkarni, R; Domingues, AF; Balayo, T; Frontini, M; Pina, C |
15-Oct-2021 | KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia | Arede, L; Foerner, E; Wind, S; Kulkarni, R; Domingues, AF; Giotopoulos, G; Kleinwaechter, S; Mollenhauer-Starkl, M; Davison, H; Chandru, A; Asby, R; Samarista, R; Gupta, S; Forte, D; Curti, A; Scheer, E; Huntly, B; Tora, L; Pina, C |
27-Jan-2020 | Loss of Kat2a Enhances Transcriptional Noise and depletes Acute Myeloid Leukaemia Stem-like Cells | Domingues, AF; Kulkarni, R; Giotopoulos, G; Gupta, S; Vinnenberg, L; Arede, L; Foerner, E; Khalili, M; Romano Adao, R; Johns, A; Tan, S; Zeka, K; Huntly, BJ; Prabakaran, S; Pina, C |
2018 | Loss of Kat2A Enhances Transcriptional Noise and Depletes Acute Myeloid Leukemia Stem-Like Cells | Domingues, AF; Kulkarni, R; Giotopoulos, G; Gupta, S; Tan, S; Foerner, E; Adao, RR; Zeka, K; Huntly, BJ; Prabakaran, S; Pina, C |
7-Jun-2023 | MAT2A inhibition in AML unveils therapeutic potential of combining DNA demethylating agents with UPR targeting | Zeka, K; Taylor, AV; Samarista, R; Ragusa, D; Suen, C-W; Cyran, OC; Domingues, AF; Meduri, E; Huntly, BJP; Forte, D; Curti, A; Pina, C |
19-Oct-2021 | Transcriptional variability accelerates pre-leukemia by cell diversification and 2 perturbation of protein synthesis | Gupta, S; Dovey, OM; Domingues, AF; Cyran, OW; Cash, CM; Giotopoulos, G; Rak, J; Cooper, J; Gozdecka, M; Asby, RJ; Al-Jabery, N; Hernandez, V; Prabakaran, S; Huntly, BJ; Vassiliou, GS; Pina, C |
3-Aug-2022 | Transcriptional variability accelerates pre-leukemia by cell diversification and perturbation of protein synthesis | Gupta, S; Dovey, OM; Domingues, AF; Cyran, OW; Cash, CM; Giotopoulos, G; Rak, J; Cooper, J; Gozdecka, M; Dijkhuis, L; Asby, RJ; Al-Jabery, N; Hernandez, V; Prabakaran, S; Huntly, BJ; Vassiliou, GS; Pina, C |