Brunel University Research Archive(BURA) preserves and enables easy and open access to all
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to publisher imposed embargoes. All awarded PhD theses are also archived on BURA.
Browsing by Author Pina, C
Showing results 1 to 20 of 20
| Issue Date | Title | Author(s) |
|---|---|---|
| 9-Nov-2022 | Alterations to Genome Organisation in Stem Cells, their Differentiation and Associated Diseases | Bridger, JM; Torres Pereira, R; Pina, C; Tosi, S; Lewis, A |
| 22-Oct-2020 | Buffering noise: KAT2A modular contributions to stabilization of transcription and cell identity in cancer and development | Arede, L; Pina, C |
| 4-Mar-2024 | Contributions of transcriptional noise to leukaemia evolution: KAT2A as a case-study | Pina, C |
| 18-Oct-2016 | A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia | Tzelepis, K; Koike-Yusa, H; De Braekeleer, E; Li, Y; Metzakopian, E; Dovey, OM; Mupo, A; Grinkevich, V; Li, M; Mazan, M; Gozdecka, M; Ohnishi, S; Cooper, J; Patel, M; McKerrell, T; Chen, B; Domingues, AF; Gallipoli, P; Teichmann, S; Ponstingl, H; McDermott, U; Saez-Rodriguez, J; Huntly, BJP; Iorio, F; Pina, C; Vassiliou, GS; Yusa, K |
| 7-Oct-2022 | Dissecting infant leukemia developmental origins with a hemogenic gastruloid model | Ragusa, D; Suen, C-W; Torregrosa Cortes, G; Dijkhuis, L; Byrne, C; Ionescu, G-A; Cerveira, J; Kranc, KR; Bigas, A; Garcia-Ojalvo, J; Martinez Arias, A; Pina, C |
| 3-Sep-2022 | Engineered model of t(7;12)(q36;p13) AML recapitulates patient-specific features and gene expression profiles | Ragusa, D; Cicirò, Y; Federico, C; Saccone, S; Bruno, F; Saeedi, R; Sisu, C; Pina, C; Sala, A; Tosi, S |
| 2021 | Exploring the combinatorial effects of targeting epigenetic modifications and molecular pathways as a therapeutic option for acute myeloid leukaemia | Samarista, Ralph Carlos |
| 27-Dec-2023 | Haematopoietic development and HSC formation in vitro: promise and limitations of gastruloid models | Dijkhuis, L; Johns, A; Ragusa, D; van den Brink, S; Pina, C |
| 15-Nov-2022 | Haemogenic Gastruloids Recapitulate Developmental Haematopoiesis and Provide an Ontogeny-Relevant Context to Dissect the Origins of Infant Leukemia | Ragusa, D; Suen, C-W; Torregrosa, G; Dijkhuis, L; Byrne, C; Balayo, T; Tavosanis, A; Durko, J; Place, K; Domingues, AF; Kranc, K; Garcia-Ojalvo, J; Martinez Arias, A; Pina, C |
| 17-Oct-2018 | Histone Acetyltransferase KAT2A Stabilizes Pluripotency with Control of Transcriptional Heterogeneity | Moris, N; Edri, S; Seyres, D; Kulkarni, R; Domingues, AF; Balayo, T; Frontini, M; Pina, C |
| 15-Oct-2021 | KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia | Arede, L; Foerner, E; Wind, S; Kulkarni, R; Domingues, AF; Giotopoulos, G; Kleinwaechter, S; Mollenhauer-Starkl, M; Davison, H; Chandru, A; Asby, R; Samarista, R; Gupta, S; Forte, D; Curti, A; Scheer, E; Huntly, B; Tora, L; Pina, C |
| 27-Jan-2020 | Loss of Kat2a Enhances Transcriptional Noise and depletes Acute Myeloid Leukaemia Stem-like Cells | Domingues, AF; Kulkarni, R; Giotopoulos, G; Gupta, S; Vinnenberg, L; Arede, L; Foerner, E; Khalili, M; Romano Adao, R; Johns, A; Tan, S; Zeka, K; Huntly, BJ; Prabakaran, S; Pina, C |
| 2018 | Loss of Kat2A Enhances Transcriptional Noise and Depletes Acute Myeloid Leukemia Stem-Like Cells | Domingues, AF; Kulkarni, R; Giotopoulos, G; Gupta, S; Tan, S; Foerner, E; Adao, RR; Zeka, K; Huntly, BJ; Prabakaran, S; Pina, C |
| 7-Jun-2023 | MAT2A inhibition in AML unveils therapeutic potential of combining DNA demethylating agents with UPR targeting | Zeka, K; Taylor, AV; Samarista, R; Ragusa, D; Suen, C-W; Cyran, OC; Domingues, AF; Meduri, E; Huntly, BJP; Forte, D; Curti, A; Pina, C |
| 30-Jan-2023 | Mechanisms associated with t(7;12) acute myeloid leukaemia: from genetics to potential treatment targets | Ragusa, D; Dijkhuis, L; Pina, C; Tosi, S |
| 25-Jan-2021 | Pan-cancer analysis of transcripts encoding novel open-reading frames (nORFs) and their potential biological functions | Erady, C; Boxall, A; Puntambekar, S; Suhas Jagannathan, N; Chauhan, R; Chong, D; Meena, N; Kulkarni, A; Kasabe, B; Prathivadi Bhayankaram, K; Umrania, Y; Andreani, A; Nel, J; Wayland, MT; Pina, C; Lilley, KS; Prabakaran, S |
| 19-Mar-2024 | Piplartine eliminates CD34+ AML stem/progenitor cells by inducing oxidative stress and suppressing NF-κB signalling | Rodrigues, ACBdaC; Silva, SLR; Dias, IRSB; Costa, RGA; Oliveira, MDS; Soares, MBP; Dias, RB; Valverde, LF; Rocha, CAG; Johnson, EM; Pina, C; Bezerra, DP |
| 19-Dec-2018 | SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4 | Tzelepis, K; De Braekeleer, E; Aspris, D; Barbieri, I; Vijayabaskar, MS; Liu, WH; Gozdecka, M; Metzakopian, E; Toop, HD; Dudek, M; Robson, SC; Hermida-Prado, F; Yang, YH; Babaei-Jadidi, R; Garyfallos, DA; Ponstingl, H; Dias, JML; Gallipoli, P; Seiler, M; Buonamici, S; Vick, B; Bannister, AJ; Rad, R; Prinjha, RK; Marioni, JC; Huntly, B; Batson, J; Morris, JC; Pina, C; Bradley, A; Jeremias, I; Bates, DO; Yusa, K; Kouzarides, T; Vassiliou, GS |
| 19-Oct-2021 | Transcriptional variability accelerates pre-leukemia by cell diversification and 2 perturbation of protein synthesis | Gupta, S; Dovey, OM; Domingues, AF; Cyran, OW; Cash, CM; Giotopoulos, G; Rak, J; Cooper, J; Gozdecka, M; Asby, RJ; Al-Jabery, N; Hernandez, V; Prabakaran, S; Huntly, BJ; Vassiliou, GS; Pina, C |
| 3-Aug-2022 | Transcriptional variability accelerates pre-leukemia by cell diversification and perturbation of protein synthesis | Gupta, S; Dovey, OM; Domingues, AF; Cyran, OW; Cash, CM; Giotopoulos, G; Rak, J; Cooper, J; Gozdecka, M; Dijkhuis, L; Asby, RJ; Al-Jabery, N; Hernandez, V; Prabakaran, S; Huntly, BJ; Vassiliou, GS; Pina, C |