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Title: An exploratory study to test the impact on three "bolt-On" items to the EQ-5D
Authors: Yang, Y
Rowen, D
Brazier, J
Tsuchiya, A
Young, T
Longworth, L
Keywords: Bolt-on;EQ-5D;Health state valuation;Hearing;Tiredness;vision
Issue Date: 2015
Publisher: Elsevier Ltd
Citation: Value in Health, 18(1): 52 - 60, (January 2015)
Abstract: Background Generic preference-based measures were criticized for being inappropriate in some conditions. One solution is to include "bolt-on" dimensions describing additional specific health problems. Objectives This study aimed to develop bolt-on dimensions to the EuroQol five-dimensional questionnaire (EQ-5D) and assess their impact on health state values. Methods Bolt-on dimensions were developed for vision problems, hearing problems, and tiredness. Each bolt-on dimension had three severity levels to match the EQ-5D. Three "core" EQ-5D states across a range of severity were selected, and each level of a bolt-on item was added, resulting in nine states in each condition. Health states with and without the bolt-on dimensions were valued by 300 members of the UK general public using time trade-off in face-to-face interviews, and mean health state values were compared using t tests. Regression analysis examined the impact of the bolt-on variants and the level of the bolt-on items after controlling for sociodemographic characteristics. Results Bolt-on dimensions had an impact on health state values of the EQ-5D; however, the size, direction, and significance of the impact depend on the severity of the core EQ-5D state and of the bolt-on dimension. Regression analysis demonstrated that after controlling for possible differences in sociodemographic characteristics between the groups, there were no significant differences in health state values between the three bolt-on dimensions but confirmed that the impact depended on the severity of the EQ-5D health state and the levels of bolt-on dimensions. Conclusions The impact of a bolt-on dimension on the EQ-5D depends on the core health state and the level of the bolt-on dimension. Further research in this area is encouraged.
Description: This article has been made available through the Brunel Open Access Publishing Fund.
ISSN: 1098-3015
Appears in Collections:Brunel OA Publishing Fund
Health Economics Research Group (HERG)

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