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Title: | An overview of recent progress in elution mode of counter current chromatography |
Authors: | Huang, X-Y Ignatova, S Hewitson, P Di, D-L |
Keywords: | Countercurrent chromatography;Elution mode;Gradient elution;Dual-mode elution;Multiple dual-mode elution;Recycling elution;Extrusion elution;Cocurrent elution;pH-zone-refining CCC |
Issue Date: | 2016 |
Publisher: | Elsevier |
Citation: | Trends in Analytical Chemistry, 77: pp. 214 - 225, (2016) |
Abstract: | Countercurrent chromatography (CCC) is a developing chromatographic technique that achieves separation based on the distribution of the target in an immiscible biphasic or multiphasic solvent system. In the past decades, this technique has advanced greatly in application and theory. This overview is mainly focused on the development of elution modes, which have been easily achieved with the classical CCC apparatus in recent years. It includes gradient elution, dual-mode elution, multiple dual-mode elution, recycling elution, extrusion elution, cocurrent elution and pH zone refining. The basic principles of each elution mode are described in detail and then summarized. The comparison and the scope of application of these elution modes are also discussed. |
URI: | http://www.sciencedirect.com/science/article/pii/S0165993615002654 http://bura.brunel.ac.uk/handle/2438/12798 |
DOI: | http://dx.doi.org/10.1016/j.trac.2015.08.006 |
ISSN: | 0165-9936 |
Appears in Collections: | Institute for the Environment |
Files in This Item:
File | Description | Size | Format | |
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Fulltext.pdf | 6.73 MB | Adobe PDF | View/Open |
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