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Title: In vitro Mycobacterial Growth Inhibition in South Korean Adults With Latent TB Infection
Authors: Lee, H
Kim, J
Kang, YA
Kim, DR
Sim, B
Zelmer, A
Fletcher, HA
Dockrell, HM
Smith, SG
Cho, S-N
Keywords: mycobacterial growth inhibition;correlates;vaccine;tuberculosis;latent tuberculosis infection
Issue Date: 26-Apr-2019
Publisher: Frontiers Media SA
Citation: Frontiers in Immunology, 10
Abstract: It is important to understand the ability to inhibit mycobacterial growth in healthy adults who would have been Bacillus Calmette-Guérin (BCG) vaccinated in childhood as this group will be the potential target population for novel booster TB vaccine trials. In this study we investigated not only the long-term immunity induced by childhood BCG vaccination but also protective immunity in terms of the ability to inhibit mycobacterial growth in those who were BCG vaccinated in childhood, with evidence of recent or remote TB infection.
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