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http://bura.brunel.ac.uk/handle/2438/7401
Title: | Synthetic studies on Terpenoid lactones |
Authors: | Toczek, Judy |
Advisors: | Lee, TV |
Issue Date: | 1985 |
Publisher: | Brunel University Institute for the Environment PhD Theses |
Abstract: | A novel stereoselective route has been developed to a vernolepin intermediate in nine steps from 2-phenylthiocyclopentenone. During this research, a regiospecific method for the alkylation of the Δ5,6 - tetrahydroindanone system has been achieved. In addition, the synthetic route demonstrates a means of differentiating between two carboxylic acid functions via a selective lactonisation. The first total ynthesis of boonein has also been completed, in 3% yield from cyclopentadiene. This route uses a chlorine atom to direct the stereo- and regiochemical outcome of most of these reaction. |
Description: | This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University. |
URI: | http://bura.brunel.ac.uk/handle/2438/7401 |
Appears in Collections: | Institute for the Environment |
Files in This Item:
File | Description | Size | Format | |
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FulltextThesis.pdf | 7.2 MB | Adobe PDF | View/Open |
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