Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/8095
Title: Protocol for an HTA report: Does therapeutic writing help people with long-term conditions? Systematic review, realist synthesis and economic modelling
Authors: Meads, C
Nyssen, OP
Wong, G
Steed, L
Bourke, L
Ross, CA
Hayman, S
Field, V
Lord, J
Greenhalgh, T
Taylor, SJ
Keywords: Long-term medical conditions;Therapeutic writing;Quality of life;Health service use
Issue Date: 2014
Publisher: BMJ Group
Citation: BMJ Open, 4(2), Article number e004377, 2014
Abstract: Introduction: Long-term medical conditions (LTCs) cause reduced health-related quality of life and considerable health service expenditure. Writing therapy has potential to improve physical and mental health in people with LTCs, but its effectiveness is not established. This project aims to establish the clinical and cost-effectiveness of therapeutic writing in LTCs by systematic review and economic evaluation, and to evaluate context and mechanisms by which it might work, through realist synthesis. Methods: Included are any comparative study of therapeutic writing compared with no writing, waiting list, attention control or placebo writing in patients with any diagnosed LTCs that report at least one of the following: relevant clinical outcomes; quality of life; health service use; psychological, behavioural or social functioning; adherence or adverse events. Searches will be conducted in the main medical databases including MEDLINE, EMBASE, PsycINFO, The Cochrane Library and Science Citation Index. For the realist review, further purposive and iterative searches through snowballing techniques will be undertaken. Inclusions, data extraction and quality assessment will be in duplicate with disagreements resolved through discussion. Quality assessment will include using Grading of Recommendations Assessment, Development and Evaluation (GRADE) criteria. Data synthesis will be narrative and tabular with meta-analysis where appropriate. De novo economic modelling will be attempted in one clinical area if sufficient evidence is available and performed according to the National Institute for Health and Care Excellence (NICE) reference case.
Description: This article is made available through the Brunel Open Access Publishing Fund. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/
URI: http://bmjopen.bmj.com/content/4/2/e004377
http://bura.brunel.ac.uk/handle/2438/8095
DOI: http://dx.doi.org/10.1136/bmjopen-2013-004377
ISSN: 2044-6055
Appears in Collections:Publications
Community Health and Public Health
Brunel OA Publishing Fund
Health Economics Research Group (HERG)

Files in This Item:
File Description SizeFormat 
Fulltext.pdf816.34 kBAdobe PDFView/Open


Items in BURA are protected by copyright, with all rights reserved, unless otherwise indicated.