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http://bura.brunel.ac.uk/handle/2438/8388
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DC Field | Value | Language |
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dc.contributor.author | Singer, AC | - |
dc.contributor.author | Howard, BM | - |
dc.contributor.author | Johnson, AC | - |
dc.contributor.author | Knowles, CJ | - |
dc.contributor.author | Jackman, S | - |
dc.contributor.author | Accinelli, C | - |
dc.contributor.author | Caracciolo, AB | - |
dc.contributor.author | Bernard, I | - |
dc.contributor.author | Bird, S | - |
dc.contributor.author | Boucard, T | - |
dc.contributor.author | Boxall, A | - |
dc.contributor.author | Brian, JV | - |
dc.contributor.author | Cartmell, E | - |
dc.contributor.author | Chubb, C | - |
dc.contributor.author | Churchley, J | - |
dc.contributor.author | Costigan, S | - |
dc.contributor.author | Crane, M | - |
dc.contributor.author | Dempsey, MJ | - |
dc.contributor.author | Dorrington, B | - |
dc.contributor.author | Ellor, B | - |
dc.contributor.author | Fick, J | - |
dc.contributor.author | Holmes, J | - |
dc.contributor.author | Hutchinson, T | - |
dc.contributor.author | Karcher, F | - |
dc.contributor.author | Kelleher, SL | - |
dc.contributor.author | Marsden, P | - |
dc.contributor.author | Noone, G | - |
dc.contributor.author | Nunn, MA | - |
dc.contributor.author | Oxford, J | - |
dc.contributor.author | Rachwal, T | - |
dc.contributor.author | Roberts, N | - |
dc.contributor.author | Roberts, M | - |
dc.contributor.author | Sacca, ML | - |
dc.contributor.author | Sanders, M | - |
dc.contributor.author | Straub, JO | - |
dc.contributor.author | Terry, A | - |
dc.contributor.author | Thomas, D | - |
dc.contributor.author | Toovey, S | - |
dc.contributor.author | Townsend, R | - |
dc.contributor.author | Vouivoulis, N | - |
dc.contributor.author | Watts, C | - |
dc.date.accessioned | 2014-05-08T08:48:27Z | - |
dc.date.available | 2014-05-08T08:48:27Z | - |
dc.date.issued | 2008 | - |
dc.identifier.citation | Environmental Health Perspectives, 116(11), 1563 - 1567, 2008 | en_US |
dc.identifier.issn | 0091-6765 | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592279/ | en |
dc.identifier.uri | http://bura.brunel.ac.uk/handle/2438/8388 | - |
dc.description | This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI. | en_US |
dc.description.abstract | On 3 October 2007, 40 participants with diverse expertise attended the workshop Tamiflu and the Environment: Implications of Use under Pandemic Conditions to assess the potential human health impact and environmental hazards associated with use of Tamiflu during an influenza pandemic. Based on the identification and risk-ranking of knowledge gaps, the consensus was that oseltamivir ethylester-phosphate (OE-P) and oseltamivir carboxylate (OC) were unlikely to pose an ecotoxicologic hazard to freshwater organisms. OC in river water might hasten the generation of OC-resistance in wildfowl, but this possibility seems less likely than the potential disruption that could be posed by OC and other pharmaceuticals to the operation of sewage treatment plants. The work-group members agreed on the following research priorities: a) available data on the ecotoxicology of OE-P and OC should be published; b) risk should be assessed for OC-contaminated river water generating OC-resistant viruses in wildfowl; c) sewage treatment plant functioning due to microbial inhibition by neuraminidase inhibitors and other antimicrobials used during a pandemic should be investigated; and d) realistic worst-case exposure scenarios should be developed. Additional modeling would be useful to identify localized areas within river catchments that might be prone to high pharmaceutical concentrations in sewage treatment plant effluent. Ongoing seasonal use of Tamiflu in Japan offers opportunities for researchers to assess how much OC enters and persists in the aquatic environment. | en_US |
dc.description.sponsorship | Environmental Knowledge Transfer Network, the Worshipful Company of Water Conservators, and the Chartered Institution of Water & Environmental Management. | en_US |
dc.language | English | - |
dc.language.iso | en | en_US |
dc.publisher | National Institute of Environmental Health Science | en_US |
dc.subject | Antiviral | en_US |
dc.subject | Drug | en_US |
dc.subject | Ecotoxicology | en_US |
dc.subject | Influenza | en_US |
dc.subject | Pandemic | en_US |
dc.subject | Pharmaceutical | en_US |
dc.subject | Pollution | en_US |
dc.subject | Sewage treatment plant | en_US |
dc.subject | Tamiflu | en_US |
dc.title | Meeting report: Risk assessment of Tamiflu use under pandemic conditions | en_US |
dc.type | Article | en_US |
dc.identifier.doi | http://dx.doi.org/10.1289/ehp.11310 | - |
pubs.organisational-data | /Brunel | - |
pubs.organisational-data | /Brunel/Brunel Active Staff | - |
pubs.organisational-data | /Brunel/Brunel Active Staff/Institute for the Environment | - |
pubs.organisational-data | /Brunel/Brunel Active Staff/Institute for the Environment/Institute for the Environment | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/Brunel Business School - URCs and Groups | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/Brunel Business School - URCs and Groups/Centre for Research into Entrepreneurship, International Business and Innovation in Emerging Markets | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Arts - URCs and Groups | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Arts - URCs and Groups/Brunel Centre for Contemporary Writing | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Brunel Institute for Ageing Studies | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Brunel Institute of Cancer Genetics and Pharmacogenomics | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Centre for Systems and Synthetic Biology | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Information Systems, Computing and Mathematics - URCs and Groups | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Information Systems, Computing and Mathematics - URCs and Groups/Multidisclipary Assessment of Technology Centre for Healthcare (MATCH) | - |
Appears in Collections: | Environment Institute for the Environment |
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