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Results 1-10 of 18 (Search time: 0.008 seconds).
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Issue DateTitleAuthor(s)
2018Loss of Kat2A Enhances Transcriptional Noise and Depletes Acute Myeloid Leukemia Stem-Like CellsDomingues, AF; Kulkarni, R; Giotopoulos, G; Gupta, S; Tan, S; Foerner, E; Adao, RR; Zeka, K; Huntly, BJ; Prabakaran, S; Pina, C
19-Dec-2018SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4Tzelepis, K; De Braekeleer, E; Aspris, D; Barbieri, I; Vijayabaskar, MS; Liu, WH; Gozdecka, M; Metzakopian, E; Toop, HD; Dudek, M; Robson, SC; Hermida-Prado, F; Yang, YH; Babaei-Jadidi, R; Garyfallos, DA; Ponstingl, H; Dias, JML; Gallipoli, P; Seiler, M; Buonamici, S; Vick, B; Bannister, AJ; Rad, R; Prinjha, RK; Marioni, JC; Huntly, B; Batson, J; Morris, JC; Pina, C; Bradley, A; Jeremias, I; Bates, DO; Yusa, K; Kouzarides, T; Vassiliou, GS
18-Oct-2016A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid LeukemiaTzelepis, K; Koike-Yusa, H; De Braekeleer, E; Li, Y; Metzakopian, E; Dovey, OM; Mupo, A; Grinkevich, V; Li, M; Mazan, M; Gozdecka, M; Ohnishi, S; Cooper, J; Patel, M; McKerrell, T; Chen, B; Domingues, AF; Gallipoli, P; Teichmann, S; Ponstingl, H; McDermott, U; Saez-Rodriguez, J; Huntly, BJP; Iorio, F; Pina, C; Vassiliou, GS; Yusa, K
25-Jan-2021Pan-cancer analysis of transcripts encoding novel open-reading frames (nORFs) and their potential biological functionsErady, C; Boxall, A; Puntambekar, S; Suhas Jagannathan, N; Chauhan, R; Chong, D; Meena, N; Kulkarni, A; Kasabe, B; Prathivadi Bhayankaram, K; Umrania, Y; Andreani, A; Nel, J; Wayland, MT; Pina, C; Lilley, KS; Prabakaran, S
22-Oct-2020Buffering noise: KAT2A modular contributions to stabilization of transcription and cell identity in cancer and developmentArede, L; Pina, C
27-Jan-2020Loss of Kat2a Enhances Transcriptional Noise and depletes Acute Myeloid Leukaemia Stem-like CellsDomingues, AF; Kulkarni, R; Giotopoulos, G; Gupta, S; Vinnenberg, L; Arede, L; Foerner, E; Khalili, M; Romano Adao, R; Johns, A; Tan, S; Zeka, K; Huntly, BJ; Prabakaran, S; Pina, C
17-Oct-2018Histone Acetyltransferase KAT2A Stabilizes Pluripotency with Control of Transcriptional HeterogeneityMoris, N; Edri, S; Seyres, D; Kulkarni, R; Domingues, AF; Balayo, T; Frontini, M; Pina, C
15-Oct-2021KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemiaArede, L; Foerner, E; Wind, S; Kulkarni, R; Domingues, AF; Giotopoulos, G; Kleinwaechter, S; Mollenhauer-Starkl, M; Davison, H; Chandru, A; Asby, R; Samarista, R; Gupta, S; Forte, D; Curti, A; Scheer, E; Huntly, B; Tora, L; Pina, C
19-Oct-2021Transcriptional variability accelerates pre-leukemia by cell diversification and 2 perturbation of protein synthesisGupta, S; Dovey, OM; Domingues, AF; Cyran, OW; Cash, CM; Giotopoulos, G; Rak, J; Cooper, J; Gozdecka, M; Asby, RJ; Al-Jabery, N; Hernandez, V; Prabakaran, S; Huntly, BJ; Vassiliou, GS; Pina, C
3-Aug-2022Transcriptional variability accelerates pre-leukemia by cell diversification and perturbation of protein synthesisGupta, S; Dovey, OM; Domingues, AF; Cyran, OW; Cash, CM; Giotopoulos, G; Rak, J; Cooper, J; Gozdecka, M; Dijkhuis, L; Asby, RJ; Al-Jabery, N; Hernandez, V; Prabakaran, S; Huntly, BJ; Vassiliou, GS; Pina, C