1. Brunel University Research Archive

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Issue DateTitleAuthor(s)
2007The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissuesPook, MA; Al-Mahdawi, S; Mouro Pinto, R; Sandi, C; Trabzuni, D
2014Epigenetic-based therapies for Friedreich ataxiaSandi, C; Sandi, M; Virmouni, SA; Al-Mahdawi, S; Pook, MA
2006GAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathologyPook, MA; Al-Mahdawi, S; Mouro Pinto, R
2012The mismatch repair system protects against intergenerational GAA repeat instability in a Friedreich ataxia mouse modelEzzatizadeh, V; Pinto, RM; Sandi, C; Sandi, M; Al-Mahdawi, S; Te Riele, H; Pook, MA
12-Jul-2021Interruptions of the FXN GAA Repeat Tract Delay the Age at Onset of Friedreich’s Ataxia in a Location Dependent MannerNethisinghe, S; Kesavan, M; Ging, H; Labrum, R; Polke, JM; Islam, S; Garcia-Moreno, H; Callaghan, MF; Cavalcanti, F; Pook, MA; Giunti, P
2015A novel GAA-repeat-expansion-based mouse model of Friedreich's ataxia.Anjomani Virmouni, S; Ezzatizadeh, V; Sandi, C; Sandi, M; Al-Mahdawi, S; Chutake, Y; Pook, MA
26-Jan-2023A new FRDA mouse model [Fxnnull:YG8s(GAA) > 800] with more than 800 GAA repeatsKalef-Ezra, E; Edzeamey, FJ; Valle, A; Khonsari, H; Kleine, P; Oggianu, C; Al-Mahdawi, S; Pook, MA; Anjomani Virmouni, S

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