Browsing by Subject Hutchinson-Gilford Progeria Syndrome

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Showing results 1 to 3 of 3
Issue DateTitleAuthor(s)
15-Jun-2018Farnesyltransferase inhibitor and rapamycin correct aberrant genome organisation and decrease DNA damage respectively, in Hutchinson–Gilford progeria syndrome fibroblastsBridger, JM
30-Apr-2019Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathwaysClements, C; Bikkul, M; Ofosu, W; Eskiw, C; Tree, D; Makarov, E; Kill, I; Bridger, JM
26-Nov-2018Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoformBikkul, MU; Faragher, RGA; Worthington, G; Meinke, P; Kerr, ARW; Sammy, A; Riyahi, K; Horton, D; Schirmer, EC; Hubank, M; Kill, IR; Anderson, RM; Slijepcevic, P; Makarov, E; Bridger, JM