Please use this identifier to cite or link to this item:
http://bura.brunel.ac.uk/handle/2438/12246
Title: | A new approach to planning in vitro and in vivo experiments for cardiovascular stents – II. Planning of experiment (abstract) |
Authors: | Atherton, M Doorly, DJ Collins, MW |
Issue Date: | 2000 |
Publisher: | Elsevier |
Citation: | Biomedicine & Pharmacotherapy, 54, (8-9): pp. 437 - 470, (2000) |
Abstract: | Within our overall project to improve the design of stents in terms of reduced rates of re-stenosis, there are three main methods, namely computer simulation and in vitro and in vivo experiments. These methods are closely integrated using contemporary design procedures described below, especially to accommodate patient-to-patient variation. Clinical experience shows that a small variation has considerable effects on flow characteristics of stents and in engineering terms may be described as a ‘geometric risk factor’. The Robust Engineering Design procedure readily incorporates this factor which may thus become a component feature in our experimental planning. We envisage that this approach could be applied to other invasive implants with a view to enhancing their quality. |
URI: | http://bura.brunel.ac.uk/handle/2438/12246 |
ISSN: | 0753-3322 http://www.journals.elsevier.com/biomedicine-and-pharmacotherapy |
Appears in Collections: | Dept of Mechanical and Aerospace Engineering Research Papers |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Fulltext.pdf | 160.64 kB | Adobe PDF | View/Open |
Items in BURA are protected by copyright, with all rights reserved, unless otherwise indicated.