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dc.contributor.authorLiu, D-
dc.contributor.authorZheng, C-
dc.contributor.authorDong, G-
dc.contributor.authorXu, C-
dc.contributor.authorDianzi, L-
dc.contributor.authorRuan, L-
dc.contributor.authorZhong, B-
dc.contributor.authorWang, B-
dc.identifier.citationMaterials Research Expressen_US
dc.description.abstractAiming to the treatment of skin burns, a new wound dressing, nanofiber mats with metal or metal oxide nanoparticles (Ag, CuO and ZnO ) , was fabricated by the electrospinning technique. During the therapeutic process, the antibacterial ability and bio-compatibility of a new dressing material are of major concerns. To expound the characteristics of EVOH nanofiber mats encapsulated with the metal or metal oxide nanoparticles, notated as Ag-EVOH, CuO-EVOH and ZnO-EVOH, respectively, for possible use as the new wound dressing materials, we have investigated the suitable processing parameters to fabricate these materials, such as the voltage, the tip-to-collector distance, the concentration of the solution, and the effect of environmental temperature. The antibacterial abilities and the bio-compatibilities of Ag-EVOH, CuO-EVOH and ZnO-EVOH were then tested and quantified. The outcomes show that the most suitable temperature for fabrication of the materials is 40℃(±3℃). Antibacterial experimental results indicate that 0.08g/ml of metal/metallic oxide shows the highest antibacterial ability on Staphylococcus aureus. And the largest diameters of bacteriastatic loops of the three kinds of nanofiber mats, ie., Ag-EVOH, CuO-EVOH and ZnO-EVOH, are 5.89mm, 5.21mm and 4.12mm, respectively. Fially, the cell proliferation of the three nanofiber mats show a similar growth trend.en_US
dc.publisherIOP Publishingen_US
dc.subjectantibacterial abilityen_US
dc.subjectcell proliferationen_US
dc.titleTemperature-controlled electrospinning of EVOH nanofibre mats encapsulated with Ag, CuO, and ZnO particles for skin wound dressingen_US
dc.relation.isPartOfMaterials Research Express-
Appears in Collections:Dept of Mechanical and Aerospace Engineering Embargoed Research Papers

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