Tensile properties of ag-EVOH electrospinning nanofiber mats for large muscle scaffolds

Abstract

Large muscle defect negatively influences people’s life, the common treatment is muscle transplantation but limited by donor source, large area wound, etc. Therefore, a muscle tissue scaffold with superimposed vascular network was developed. For ensuring the performance of fascia layer which alternated by poly(ethylene-co-vinyl alcohol) (EVOH) nanofiber mats encapsulated with Ag, the mechanical properties and water vapor transmission of different samples (7.5%, 10%, 12.5% EVOH solution densities with 0.02, 0.05, 0.08 g/ml of Ag, respectively) were mainly discussed. Meanwhile, the main parameters (voltage, tip-to-collector distance, solution density, concentration of Ag) were compared to find their influence on fabricating nanofibers.