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DC Field | Value | Language |
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dc.contributor.author | Giudici, A | - |
dc.contributor.author | Khir, AW | - |
dc.contributor.author | Reesink, KD | - |
dc.contributor.author | Delhaas, T | - |
dc.contributor.author | Spronck, B | - |
dc.date.accessioned | 2021-07-20T13:40:29Z | - |
dc.date.available | 2021-07-20T13:40:29Z | - |
dc.date.issued | 2021-07-15 | - |
dc.identifier.citation | Giudici, A. Khir, A.W., Reesink, K.D.., Delhaas, T., and Spronck, B. (2021) 'Five years of cardio-ankle vascular index (CAVI) and CAVI0: how close are we to a pressure-independent index of arterial stiffness?', Journal of Hypertension, 0, (in press), pp. 1 - 11. doi: 10.1097/HJH.0000000000002928. | en_US |
dc.identifier.issn | 0263-6352 | - |
dc.identifier.uri | https://bura.brunel.ac.uk/handle/2438/22973 | - |
dc.description.abstract | Copyright © 2021 The Author(s). Pulse wave velocity, a common metric of arterial stiffness, is an established predictor for cardiovascular events and mortality. However, its intrinsic pressure-dependency complicates the discrimination of acute and chronic impacts of increased blood pressure on arterial stiffness. Cardio-ankle vascular index (CAVI) represented a significant step towards the development of a pressure-independent arterial stiffness metric. However, some potential limitations of CAVI might render this arterial stiffness metric less pressure-independent than originally thought. For this reason, we later introduced CAVI0. Nevertheless, advantages of one approach over the other are left debated. This review aims to shed light on the pressure (in)dependency of both CAVI and CAVI0. By critically reviewing results from studies reporting both CAVI and CAVI0 and using simple analytical methods, we show that CAVI0 may enhance the pressure-independent assessment of arterial stiffness, especially in the presence of large inter-individual differences in blood pressure. | en_US |
dc.description.sponsorship | European Union’s Horizon 2020 Research and Innovation program (grant 793805 to B.S.). | en_US |
dc.format.extent | 2128 - 2138 (11) | - |
dc.format.medium | Print-Electronic | - |
dc.language.iso | en_US | en_US |
dc.publisher | Wolters Kluwer Health, Inc. | en_US |
dc.rights | Copyright © 2021 The Author(s). This is an-open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | - |
dc.subject | arterial stiffness | en_US |
dc.subject | cardio-ankle vascular index | en_US |
dc.subject | CAVI0 | en_US |
dc.subject | pressure-dependency | en_US |
dc.subject | pulse wave velocity | en_US |
dc.title | Five years of cardio-ankle vascular index (CAVI) and CAVI0: how close are we to a pressure-independent index of arterial stiffness? | en_US |
dc.type | Article | en_US |
dc.identifier.doi | https://doi.org/10.1097/hjh.0000000000002928 | - |
dc.relation.isPartOf | Journal of Hypertension | - |
pubs.issue | 11 | - |
pubs.publication-status | Published | - |
pubs.volume | 31 | - |
dc.identifier.eissn | 1473-5598 | - |
Appears in Collections: | Dept of Mechanical and Aerospace Engineering Research Papers |
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