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Title: Estrogenic potency of effluent from two sewage treatment works in the United Kingdom
Authors: Harries, JE
Janbakhsh, A
Jobling, S
Matthiessen, P
Sumpter, JP
Tyler, CR
Keywords: Estrogen, Sewage, Vitellogenin, Rainbow trout
Issue Date: 1999
Publisher: Society of Environmental Toxicology and Chemistry Press
Citation: Environmental Toxicology and Chemistry. 18 (5) 932–937
Abstract: Rainbow trout were exposed for 3 weeks (in a flow-through system) to various dilutions of treated effluent (25, 50, 75, and 100%) from Harpenden and Chelmsford sewage treatment works (STW) during November 1994 and August 1996, respectively, and the induction of plasma vitellogenin was measured. Significant (p < 0.05) increases in plasma vitellogenin concentrations occurred in fish held in effluent from Harpenden STW at concentrations of 50% and above. At Chelmsford STW, the effluent appeared to be more potent, causing induction of vitellogenin in fish at concentrations as low as 25% (compared with 50% for the Harpenden effluent). Exposure to lower concentrations of effluent emanating from Chelmsford in April of the following year indicated that estrogenic activity was diluted to no-effect levels at this STW at concentrations between 12 and 25%.
ISSN: 0730-7268
Appears in Collections:Environment
Institute for the Environment

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