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Title: Toroidal coil chromatography: The effect of scale-up and "g" field on stage efficiency
Authors: Sutherland, IA
Hewitson, P
De Folter, J
Keywords: Process scale;Toroidal coil chromatography;TCC
Issue Date: 2010
Publisher: Springer BV
Citation: Journal of Chromatography A, 1218(36): 6144–6147, Dec 2010
Abstract: Selected test results have been taken from various publications and resolution and stage efficiency measured using an established model. All experiments used the same sample and, where possible, the same sample loading. The results show that stage mixing efficiencies have increased from 1.1% in 1998 to greater than 25% in the latest scaled-up version of a Toroidal coil chromatography (TCC) instrument working at 240g.
Description: This work was supported by the UK BBSRC (Follow-on Grant No. BB/FOF/206) following on from the BBSRC protein purification study (DEMPRO-Grant No. BB/C506364/1). This article is available from the specified link - Copyright @ 2010 Springer BV
ISSN: 1873-3778
Appears in Collections:Brunel Institute for Bioengineering (BIB)
Brunel OA Publishing Fund

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