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http://bura.brunel.ac.uk/handle/2438/5617
Title: | Toroidal coil chromatography: The effect of scale-up and "g" field on stage efficiency |
Authors: | Sutherland, IA Hewitson, P De Folter, J |
Keywords: | Process scale;Toroidal coil chromatography;TCC |
Issue Date: | 2010 |
Publisher: | Springer BV |
Citation: | Journal of Chromatography A, 1218(36): 6144–6147, Dec 2010 |
Abstract: | Selected test results have been taken from various publications and resolution and stage efficiency measured using an established model. All experiments used the same sample and, where possible, the same sample loading. The results show that stage mixing efficiencies have increased from 1.1% in 1998 to greater than 25% in the latest scaled-up version of a Toroidal coil chromatography (TCC) instrument working at 240g. |
Description: | This work was supported by the UK BBSRC (Follow-on Grant No. BB/FOF/206) following on from the BBSRC protein purification study (DEMPRO-Grant No. BB/C506364/1). This article is available from the specified link - Copyright @ 2010 Springer BV |
URI: | http://www.sciencedirect.com/science/article/pii/S0021967310018017 http://bura.brunel.ac.uk/handle/2438/5617 |
DOI: | http://dx.doi.org/10.1016/j.chroma.2010.12.090 |
ISSN: | 1873-3778 |
Appears in Collections: | Brunel Institute for Bioengineering (BIB) Publications Brunel OA Publishing Fund |
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