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Title: Near wall hemodynamics: Modelling the glycocalyx and the endothelial surface
Authors: Pontrelli, G
Halliday, I
Spencer, TJ
Care, CM
König, CS
Collins, MW
3rd Micro and Nano Flows Conference (MNF2011)
Keywords: Microcirculation;Glycocalyx;Lattice Boltzmann method;Multi-component fluid;Endothelium
Issue Date: 2011
Publisher: Brunel University
Citation: 3rd Micro and Nano Flows Conference, Thessaloniki, Greece, 22-24 August 2011
Abstract: In this paper a coarse-grained model for blood flow in small arteries is presented. Blood is modelled as a two-component incompressible fluid: the plasma and corpuscular elements dispersed in it. The latter are modelled as deformable liquid droplets having greater density and viscosity. Interfacial surface tension and membrane effects are present to mimic key properties and to avoid droplets’ coalescence. The mesoscopic model also includes the presence of the wavy wall, due to the endothelial cells and incorporates a representation of the glycocalyx, covering the vessel wall. The glycocalyx is modelled as a porous medium, the droplets being subjected to a repulsive elastic force when approaching it, during their transit. Preliminary simulations are intended to show the influence of the undulation on the wall together with that of the glycocalyx.
Description: This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, Aristotle University of Thessaloniki, University of Thessaly, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute.
ISBN: 978-1-902316-98-7
Appears in Collections:Brunel Institute for Bioengineering (BIB)

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