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Title: | A new approach to planning in vitro and in vivo experiments for cardiovascular stents. (2) Planning of experiments |
Authors: | Atherton, MA Doorly, DJ Collins, MW Sigwart, U |
Issue Date: | 2000 |
Publisher: | Pacini Editore SpA |
Citation: | Internal Medicine : Clinical and Laboratory, 8(2): 31 - 35, 2000 |
Abstract: | Within our overall project to improve the design of stents in terms of reduced rates of re-stenosis, there are three main methods, namely computer simulation and in vitro and in vivo experiments. These methods are closely integrated using contemporary design procedures described below, especially to accommodate patient-to-patient variation. Clinical experience shows that a small variation has considerable effects on flow characteristics of stents and in engineering terms may be described as a ‘geometric risk factor’. The Robust Engineering Design procedure readily incorporates this factor which may thus become a component feature in our experimental planning. We envisage that this approach could be applied to other invasive implants with a view to enhancing their quality. |
Description: | Copyright @ 2000 Pacini Editore SpA |
URI: | http://bura.brunel.ac.uk/handle/2438/7606 |
ISSN: | 1590-9271 |
Appears in Collections: | Publications Mechanical and Aerospace Engineering Dept of Mechanical and Aerospace Engineering Research Papers |
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