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DC Field | Value | Language |
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dc.contributor.author | Yeh, R-G | - |
dc.contributor.author | Lin, C-W | - |
dc.contributor.author | Abbod, MF | - |
dc.contributor.author | Shieh, J-S | - |
dc.date.accessioned | 2014-03-24T11:27:11Z | - |
dc.date.available | 2014-03-24T11:27:11Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Computational and Mathematical Methods in Medicine, 2012 Article 947191, 2012 | en_US |
dc.identifier.issn | 1748-670X | - |
dc.identifier.uri | http://www.hindawi.com/journals/cmmm/2012/947191/ | en |
dc.identifier.uri | http://bura.brunel.ac.uk/handle/2438/8172 | - |
dc.description | Copyright © 2012 Rong-Guan Yeh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | en_US |
dc.description.abstract | A detrended fluctuation analysis (DFA) method is applied to image analysis. The 2-dimensional (2D) DFA algorithms is proposed for recharacterizing images of lymph sections. Due to Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL), there is a significant different 5-year survival rates after multiagent chemotherapy. Therefore, distinguishing the difference between BL and DLBCL is very important. In this study, eighteen BL images were classified as group A, which have one to five cytogenetic changes. Ten BL images were classified as group B, which have more than five cytogenetic changes. Both groups A and B BLs are aggressive lymphomas, which grow very fast and require more intensive chemotherapy. Finally, ten DLBCL images were classified as group C. The short-term correlation exponent α1 values of DFA of groups A, B, and C were 0.370 ± 0.033, 0.382 ± 0.022, and 0.435 ± 0.053, respectively. It was found that α1 value of BL image was significantly lower (P < 0.05) than DLBCL. However, there is no difference between the groups A and B BLs. Hence, it can be concluded that α1 value based on DFA statistics concept can clearly distinguish BL and DLBCL image. | en_US |
dc.description.sponsorship | National Science Council (NSC) of Taiwan the Center for Dynamical Biomarkers and Translational Medicine, National Central University, Taiwan (also sponsored by National Science Council). | en_US |
dc.language | English | - |
dc.language.iso | en | en_US |
dc.publisher | Hindawi Publishing Corporation | en_US |
dc.subject | Burkitt lymphoma | en_US |
dc.subject | Diffuse large B-cell lymphoma | en_US |
dc.subject | Detrended fluctuation analysis | en_US |
dc.subject | Image analysis | en_US |
dc.title | Two-dimensional matrix algorithm using detrended fluctuation analysis to distinguish Burkitt and diffuse large B-cell lymphoma | en_US |
dc.type | Article | en_US |
dc.identifier.doi | http://dx.doi.org/10.1155/2012/947191 | - |
pubs.organisational-data | /Brunel | - |
pubs.organisational-data | /Brunel/Brunel Active Staff | - |
pubs.organisational-data | /Brunel/Brunel Active Staff/School of Engineering & Design | - |
pubs.organisational-data | /Brunel/Brunel Active Staff/School of Engineering & Design/Electronic and Computer Engineering | - |
pubs.organisational-data | /Brunel/Group Publication Pages | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Engineering and Design - URCs and Groups | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Engineering and Design - URCs and Groups/Centre for Electronics Systems Research | - |
Appears in Collections: | Electronic and Electrical Engineering Publications Dept of Electronic and Electrical Engineering Research Papers |
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Fulltext.pdf | 7.51 MB | Adobe PDF | View/Open |
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