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http://bura.brunel.ac.uk/handle/2438/8930
Title: | The EXACT description of biomedical protocols |
Authors: | Soldatova, LN Aubrey, W King, RD Clare, A |
Keywords: | Experiment protocols;Biological laboratory protocols;Experiment ACTions ontology;Laboratory science |
Issue Date: | 2008 |
Publisher: | Oxford University Press |
Citation: | Bioinformatics, 24(13), I295 - I303, 2008 |
Abstract: | Motivation: Many published manuscripts contain experiment protocols which are poorly described or deficient in information. This means that the published results are very hard or impossible to repeat. This problem is being made worse by the increasing complexity of high-throughput/automated methods. There is therefore a growing need to represent experiment protocols in an efficient and unambiguous way. Results: We have developed the Experiment ACTions (EXACT) ontology as the basis of a method of representing biological laboratory protocols. We provide example protocols that have been formalized using EXACT, and demonstrate the advantages and opportunities created by using this formalization. We argue that the use of EXACT will result in the publication of protocols with increased clarity and usefulness to the scientific community. Availability: The ontology, examples and code can be downloaded from http://www.aber.ac.uk/compsci/Research/bio/dss/EXACT/ |
Description: | © 2008 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
URI: | http://bioinformatics.oxfordjournals.org/content/24/13/i295 http://bura.brunel.ac.uk/handle/2438/8930 |
DOI: | http://dx.doi.org/10.1093/bioinformatics/btn156 |
ISSN: | 1367-4803 |
Appears in Collections: | Computer Science Dept of Computer Science Research Papers |
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