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Please use this identifier to cite or link to this item:
http://bura.brunel.ac.uk/handle/2438/9016Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Planes, FJ | - |
| dc.contributor.author | Beasley, JE | - |
| dc.date.accessioned | 2014-09-08T14:22:59Z | - |
| dc.date.available | 2014-09-08T14:22:59Z | - |
| dc.date.issued | 2009 | - |
| dc.identifier.citation | Bioinformatics, 25(20), 2723 - 2729, 2009 | en_US |
| dc.identifier.issn | 1367-4803 | - |
| dc.identifier.uri | http://bioinformatics.oxfordjournals.org/content/25/20/2723 | en |
| dc.identifier.uri | http://bura.brunel.ac.uk/handle/2438/9016 | - |
| dc.description | This article is available open access through the publisher’s website through the link below. Copyright @ The Author 2009. | en_US |
| dc.description.abstract | Motivation: Different mathematical methods have emerged in the post-genomic era to determine metabolic pathways. These methods can be divided into stoichiometric methods and path finding methods. In this paper we detail a novel optimization model, based upon integer linear programming, to determine metabolic pathways. Our model links reaction stoichiometry with path finding in a single approach. We test the ability of our model to determine 40 annotated Escherichia coli metabolic pathways. We show that our model is able to determine 36 of these 40 pathways in a computationally effective manner. Contact: john.beasley@brunel.ac.uk Supplementary information: Supplementary data are available at Bioinformatics online (http://bioinformatics.oxfordjournals.org/cgi/content/full/btp441/DC1). | en_US |
| dc.language | English | - |
| dc.language.iso | en | en_US |
| dc.publisher | Oxford University Press | en_US |
| dc.subject | Metabolic pathways | en_US |
| dc.subject | Integer linear programming | en_US |
| dc.subject | Optimization model | en_US |
| dc.subject | Escherichia coli metabolic pathways | en_US |
| dc.title | An optimization model for metabolic pathways | en_US |
| dc.type | Article | en_US |
| dc.identifier.doi | http://dx.doi.org/10.1093/bioinformatics/btp441 | - |
| pubs.organisational-data | /Brunel | - |
| pubs.organisational-data | /Brunel/Group Publication Pages | - |
| pubs.organisational-data | /Brunel/Leavers | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/Brunel Business School - URCs and Groups | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/Brunel Business School - URCs and Groups/Centre for Research into Entrepreneurship, International Business and Innovation in Emerging Markets | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Arts - URCs and Groups | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Arts - URCs and Groups/Brunel Centre for Contemporary Writing | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Brunel Institute for Ageing Studies | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Brunel Institute of Cancer Genetics and Pharmacogenomics | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Centre for Systems and Synthetic Biology | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Information Systems, Computing and Mathematics - URCs and Groups | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Information Systems, Computing and Mathematics - URCs and Groups/Multidisclipary Assessment of Technology Centre for Healthcare (MATCH) | - |
| Appears in Collections: | Dept of Mathematics Research Papers Mathematical Sciences | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Notice.pdf | 38.6 kB | Adobe PDF | View/Open |
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