Please use this identifier to cite or link to this item:
http://bura.brunel.ac.uk/handle/2438/9038
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DC Field | Value | Language |
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dc.contributor.author | Paul, S | - |
dc.contributor.author | Paul, D | - |
dc.contributor.author | Fern, GR | - |
dc.contributor.author | Ray, AK | - |
dc.date.accessioned | 2014-09-09T11:24:01Z | - |
dc.date.available | 2014-09-09T11:24:01Z | - |
dc.date.issued | 2011 | - |
dc.identifier.citation | Journal of the Royal Society Interface, 8(61), 1204 - 1211, 2011 | en_US |
dc.identifier.issn | 1742-5689 | - |
dc.identifier.uri | http://rsif.royalsocietypublishing.org/content/8/61/1204 | en |
dc.identifier.uri | http://bura.brunel.ac.uk/handle/2438/9038 | - |
dc.description | This article is available open access through the publisher’s website at the link below. Copyright @ 2011 The Royal Society. | en_US |
dc.description.abstract | The detection sensitivity of silver nanoparticle (AgNP)-tagged goat immunoglobulin G (gIgG) microarrays was investigated by studying surface plasmon resonance (SPR) images captured in the visible wavelength range with the help of a Kretchmann-configured optical coupling set-up. The functionalization of anti-gIgG molecules on the AgNP surface was studied using transmission electron microscopy, photon correlation measurements and UV–visible absorption spectroscopy. A value of 1.3 × 107 M−1 was obtained for the antibody–antigen binding constant by monitoring the binding events at a particular resonance wavelength. The detection limit of this SPR imaging instrument is 6.66 nM of gIgG achieved through signal enhancement by a factor of larger than 4 owing to nanoparticle tagging with the antibody. | en_US |
dc.description.sponsorship | The European Commission | en_US |
dc.language | English | - |
dc.language.iso | en | en_US |
dc.publisher | The Royal Society | en_US |
dc.subject | Plasmonics | en_US |
dc.subject | Antibody microarray | en_US |
dc.subject | Nanoparticle labelling | en_US |
dc.title | Surface plasmon resonance imaging detection of silver nanoparticle-tagged immunoglobulin | en_US |
dc.type | Article | en_US |
dc.identifier.doi | http://dx.doi.org/10.1098/rsif.2010.0747 | - |
pubs.organisational-data | /Brunel | - |
pubs.organisational-data | /Brunel/Brunel Staff by College/Department/Division | - |
pubs.organisational-data | /Brunel/Brunel Staff by College/Department/Division/College of Engineering, Design and Physical Sciences | - |
pubs.organisational-data | /Brunel/Brunel Staff by College/Department/Division/College of Engineering, Design and Physical Sciences/Dept of Mechanical, Aerospace and Civil Engineering | - |
pubs.organisational-data | /Brunel/Brunel Staff by College/Department/Division/College of Engineering, Design and Physical Sciences/Dept of Mechanical, Aerospace and Civil Engineering/Mechanical and Aerospace Engineering | - |
pubs.organisational-data | /Brunel/Brunel Staff by Institute/Theme | - |
pubs.organisational-data | /Brunel/Brunel Staff by Institute/Theme/Institute of Materials and Manufacturing | - |
pubs.organisational-data | /Brunel/Brunel Staff by Institute/Theme/Institute of Materials and Manufacturing/Materials Characterisation and Processing | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/Brunel Business School - URCs and Groups | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/Brunel Business School - URCs and Groups/Centre for Research into Entrepreneurship, International Business and Innovation in Emerging Markets | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Brunel Institute for Ageing Studies | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Brunel Institute of Cancer Genetics and Pharmacogenomics | - |
pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Centre for Systems and Synthetic Biology | - |
Appears in Collections: | Wolfson Centre for Sustainable Materials Development and Processing Dept of Mechanical and Aerospace Engineering Research Papers |
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Notice.pdf | 40.54 kB | Adobe PDF | View/Open |
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