The ability of subsurface dams to protect freshwater abstraction wells against seawater intrusion in heterogeneous aquifers See

The main purpose of this study was to examine the ability of subsurface dams to protect freshwater abstraction against seawater intrusion in both homogeneous and layered aquifers. Laboratory experiments were conducted in a synthetic aquifer where a subsurface dam was simulated in a ...

Effect of prolonged natural ageing on microstructure and tensile properties of a high strength die-cast Al-Mg-Si-Zn alloy See

A two-year prolonged natural ageing effect of a high strength and heat treatment-free Al5.5Mg2Si3Zn die-cast alloy was investigated, and the microstructure was characterized to understand the underlying mechanisms of high strength in the as-cast state and the strong natural ageing strengthening.&...

Decision Frameworks for Assessing Cost-Effectiveness Given Previous Nonoptimal Decisions See

Introduction: Economic evaluations identify the best course of action by a decision maker with respect to the level of health within the overall population. Traditionally, they identify 1 optimal treatment choice. In many jurisdictions, multiple technologies can be covered for the...

The development of a temporary cardiac pacing simulator: A training tool to enhance the management of post cardiac surgical patient care See

Temporary cardiac pacing (TP) is essential for managing haemodynamically unstable arrhythmias following cardiac surgery, yet its effectiveness depends on precise manual adjustments by clinicians. Despite its critical role, TP training remains inconsistent due to a lack of formal guideline...

Brexit voters: Who has changed their mind? See

We analyse which demographic groups in the UK were more likely to change their views on Brexit following the 2016 referendum on EU membership. Drawing on a large individual-level dataset of over 12,000 respondents, we find that women and middle-aged individuals were significantly m...

Investigating the suitability of locally available materials to develop low-carbon cementitious materials for 3D printing applications See

The environmental impact of traditional OPC has driven the search for sustainable alternatives like alkali-activated materials, calcined clay blends, and recycled aggregates. This doctoral research explores low-carbon cementitious materials using locally sourced construction waste. The work is divided into...

Targeting Peptidyl Arginine Deiminase 4 and NADPH Oxidase Pathways Regulates Neutrophil Dependent Thrombo-inflammation See

Introduction/Background & aims: Excessive neutrophil extracellular trap (NET) production is associated with the pathogenesis of thrombo-inflammatory diseases e.g. sickle cell disease (SCD), and is catalyzed by the enzyme Peptidyl Arginine Deiminase-4 (PAD4). Neutrophil reactive oxygen species (ROS), es...

Reusable Packaging Systems: Design recommendations for fostering and sustaining consumer adoption See

Multiple factors influence the success and sustainability of reusable packaging systems, including consumer behaviour (Bradley & Corsini, 2023). Recent findings from UK trials emphasise the need for continued consumer engagement to ensure reusable packaging systems are profitable and provide ...

Implementing reusable packaging systems: Lessons from industry See

Despite corporate pledges, reliance on singleuse plastics continues to grow (Greenpeace, 2018). In 2023, plastic production reached 413.8mT (Plastics Europe, 2024), with a predicted 152.5mT attributed to plastic packaging (OECD, 2022). An estimated 50% of plastic packaging enters landfill each ye...