An Adaptive-Intelligent Distance-Aware Approach for Dynamic Network Connectivity See

Optimizing network connectivity characterizes a major challenge in different applications, e.g. IoT, where the efficiency of connectivity under constraints like distance and adaptability is essential. The key objective of the Minimum Spanning Tree (MST) methods is to construct a subset of&#...

Evaluating Patient and Public Involvement and Engagement Activity Within the 3DPiPPIn Trial: A Qualitative Exploration of Contributors' Perspectives on Their Impact See

Introduction: Patient and Public Involvement and Engagement (PPIE) is now considered essential to the delivery of high-quality, patient-centred and translational research. However, despite widespread recognition of this, PPIE remains poorly understood, inconsistently utilised and inadequately reported. &...

Synuclein Disorder‐Related Genetic Determinants of Mild Behavioural Impairment in a Pre‐Clinical Community Cohort See

Background: The GBA variant confers increased risk of synuclein disorders but it is unclear what impact it has in pre-clinical groups. This study aimed to identify early psychiatric and cognitive manifestations amongst pre-clinical GBA carriers in a community cohort. Meth...

Neuropsychiatric symptoms and their impact on cognitive functioning in patients with Parkinson's disease: A systematic review of the literature See

Parkinson's disease (PD) is a progressive, neurodegenerative disorder that affects the dopaminergic system and is characterized by motor and nonmotor symptoms, which affect the quality of life. Among these, neuropsychiatric symptoms (NPS), such as depression, hallucinations, and apathy, are common...

Development and Cross‐Sectional Validation of the Quality of Life and Function Five‐Domain Scale (QFS‐5) in Dementia‐Free Community‐Dwelling Older Adults See

Introduction: Quality of life (QoL) captures objective life conditions, subjective wellbeing, and personal aspirations. Interest is growing in ability-based, patient-centered instruments, not confounded by health outcomes. The Quality of Life and Function Five Domain Scale (QFS-5) uses a multi-...

Effect of polygenic risk scores for Alzheimer's disease on brain structure, cerebrospinal fluid, and cognition See

Background: Apolipoprotein E (APOE) is the most studied gene in relation to, and has the strongest genetic association with, sporadic Alzheimer’s disease (AD). The APOE epsilon 4 (ɛ4) risk variant is found in approximately 14% of the general population and in approximately 37% of&#...

‘Trust the process’: New teacher experiences of instructional coaching as an element of their teacher training in England See

This study aimed to better understand new teacher experiences of instructional coaching as an element of their teacher training in England. The research questions examined teacher experience on three levels: in relation to their developing professional identity and agency; in relation to...

The legal protection of disabled women under Qatari law and international commitments See

This thesis examines the legal protection of women with disabilities in Qatar through the interaction of domestic law, international human rights law, and Shari’ah law. While existing scholarship recognises the intersecting forms of discrimination faced by women with disabilities on the basi...

Why teach curriculum music to children in primary school? An exploration of primary teachers’ perceptions of music in the school curriculum See

Research has identified that music can be considered a difficult subject to teach in primary schools because of the specificity of musical expertise (Rogers et al., 2008). A range of individual factors have been found to impact on the teaching practices of primary teachers&#x...