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DC Field | Value | Language |
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dc.contributor.author | Ryan, JM | - |
dc.contributor.author | Crowley, VE | - |
dc.contributor.author | Hensey, O | - |
dc.contributor.author | McGahey, A | - |
dc.contributor.author | Gormley, J | - |
dc.date.accessioned | 2015-02-06T12:07:27Z | - |
dc.date.available | 2015-02-06T12:07:27Z | - |
dc.date.issued | 2014-04-14 | - |
dc.identifier.citation | Ryan, J.M., Crowley, V.E., Hensey, O., McGahey, A. and Gormley, J. (2014) 'Waist Circumference Provides an Indication of Numerous Cardiometabolic Risk Factors in Adults With Cerebral Palsy', Archives of Physical Medicine and Rehabilitation, 95(8), pp. 1540-1546. doi: 10.1016/j.apmr.2014.03.029. | en_US |
dc.identifier.issn | 0003-9993 | - |
dc.identifier.uri | https://bura.brunel.ac.uk/handle/2438/10141 | - |
dc.description | This article has been made available through the Brunel Open Access Publishing Fund. | - |
dc.description.abstract | Objective: To report the prevalence of cardiometabolic risk factors in a cohort of adults with cerebral palsy (CP) and to investigate the ability of anthropometric measures to predict these factors. Design: Cross-sectional study. Setting: Testing took place in a laboratory setting. Participants: Adults with CP (NZ55; mean age, 37.5 13.3y; Gross Motor Function Classification System levels, IeV) participated in this study. Interventions: Not applicable. Main Outcome Measures: Total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, glucose, insulin, and C-reactive protein levels were measured from a fasting venous blood sample. Insulin resistance was calculated using the Homeostasis Model Assessment (HOMA-IR) index. Blood pressure, body mass index (BMI), waist circumference (WC), waist-hip ratio, and waist-height ratio were also measured. The metabolic syndrome (MetS) was defined according to the 2009 Joint Interim Statement. Results: The prevalence of the MetS was 20.5% in ambulatory adults and 28.6% in nonambulatory adults. BMI was associated with HOMA-IR only (bZ.451; P<.01). WC was associated with HOMA-IR (bZ.480; P<.01), triglycerides (bZ.450; P<.01), and systolic blood pressure (bZ.352; P<.05). Receiver operating characteristic curve analysis revealed that WC provided the best indication of hypertensive blood pressure, dyslipidemia, HOMA-IR, and the presence of multiple risk factors (area under the curve, .713e.763). Conclusions: A high prevalence of the MetS was observed in this relatively young sample of adults with CP. WC was a better indicator of a number of risk factors than was BMI and presents as a clinically useful method of screening for cardiometabolic risk among adults with CP. | en_US |
dc.format.medium | Print-Electronic | - |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | Copyright © 2014 by the American Congress of Rehabilitation Medicine Open access under CC BY-NC-ND license. | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | - |
dc.subject | risk factors | en_US |
dc.subject | cerebral palsy | en_US |
dc.subject | body mass index | - |
dc.subject | metabolic syndrome X | - |
dc.subject | rehabilitation | - |
dc.subject | waist circumference | - |
dc.title | Waist circumference provides an indication of numerous cardiometabolic risk factors in adults with cerebral palsy | en_US |
dc.type | Article | en_US |
dc.identifier.doi | https://doi.org/10.1016/j.apmr.2014.03.029 | - |
dc.relation.isPartOf | Archives of Physical Medicine and Rehabilitation | - |
dc.relation.isPartOf | Archives of Physical Medicine and Rehabilitation | - |
pubs.organisational-data | /Brunel | - |
pubs.organisational-data | /Brunel/Brunel Staff by College/Department/Division | - |
pubs.organisational-data | /Brunel/Brunel Staff by College/Department/Division/College of Health and Life Sciences | - |
pubs.organisational-data | /Brunel/Brunel Staff by College/Department/Division/College of Health and Life Sciences/Dept of Clinical Sciences | - |
pubs.organisational-data | /Brunel/Brunel Staff by College/Department/Division/College of Health and Life Sciences/Dept of Clinical Sciences/Physiotherapy | - |
pubs.organisational-data | /Brunel/Brunel Staff by Institute/Theme | - |
pubs.organisational-data | /Brunel/Brunel Staff by Institute/Theme/Institute of Environmental, Health and Societies | - |
pubs.organisational-data | /Brunel/Brunel Staff by Institute/Theme/Institute of Environmental, Health and Societies/Healthy Ageing | - |
dc.identifier.eissn | 1532-821X | - |
Appears in Collections: | Biological Sciences Brunel OA Publishing Fund Dept of Life Sciences Research Papers |
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