Please use this identifier to cite or link to this item:
http://bura.brunel.ac.uk/handle/2438/13206
Title: | Similar Inflammatory Responses following Sprint Interval Training Performed in Hypoxia and Normoxia |
Authors: | Richardson, AJ Relf, RL Saunders, A Gibson, OR |
Keywords: | High intensity training;Altitude;Endurance;Inflammation;Cytokine |
Issue Date: | 2016 |
Publisher: | Frontiers Media |
Citation: | Frontiers in Physiology, 7:332, pp. 1-10, (2016) |
Abstract: | Sprint interval training (SIT) is an efficient intervention capable of improving aerobic capacity and exercise performance. This experiment aimed to determine differences in training adaptations and the inflammatory responses following 2 weeks of SIT (30 s maximal work, 4 min recovery; 4–7 repetitions) performed in normoxia or hypoxia. Forty-two untrained participants [(mean ± SD), age 21 ±1 years, body mass 72.1 ±11.4 kg, and height 173 ±10 cm] were equally and randomly assigned to one of three groups; control (CONT; no training, n = 14), normoxic (NORM; SIT in FiO2: 0.21, n = 14), and normobaric hypoxic (HYP; SIT in FiO2: 0.15, n = 14). Participants completed a V ˙ O 2peak V˙O2peak test, a time to exhaustion (TTE) trial (power = 80% V ˙ O 2peak V˙O2peak) and had hematological [hemoglobin (Hb), haematocrit (Hct)] and inflammatory markers [interleukin-6 (IL-6), tumor necrosis factor-α (TNFα)] measured in a resting state, pre and post SIT. V ˙ O 2peak V˙O2peak (mL.kg−1.min−1) improved in HYP (+11.9%) and NORM (+9.8%), but not CON (+0.9%). Similarly TTE improved in HYP (+32.2%) and NORM (+33.0%), but not CON (+3.4%) whilst the power at the anaerobic threshold (AT; W.kg−1) also improved in HYP (+13.3%) and NORM (+8.0%), but not CON (–0.3%). AT (mL.kg−1.min−1) improved in HYP (+9.5%), but not NORM (+5%) or CON (–0.3%). No between group change occurred in 30 s sprint performance or Hb and Hct. IL-6 increased in HYP (+17.4%) and NORM (+20.1%), but not CON (+1.2%), respectively. TNF-α increased in HYP (+10.8%) NORM (+12.9%) and CON (+3.4%). SIT in HYP and NORM increased V ˙ O 2peak V˙O2peak, power at AT and TTE performance in untrained individuals, improvements in AT occurred only when SIT was performed in HYP. Increases in IL-6 and TNFα reflect a training induced inflammatory response to SIT; hypoxic conditions do not exacerbate this. |
URI: | http://journal.frontiersin.org/article/10.3389/fphys.2016.00332/full http://bura.brunel.ac.uk/handle/2438/13206 |
DOI: | http://dx.doi.org/10.3389/fphys.2016.00332 |
ISSN: | 1664-042X |
Appears in Collections: | Dept of Life Sciences Research Papers |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Fulltext.pdf | 1.41 MB | Adobe PDF | View/Open |
Items in BURA are protected by copyright, with all rights reserved, unless otherwise indicated.