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http://bura.brunel.ac.uk/handle/2438/13245
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DC Field | Value | Language |
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dc.contributor.author | Gopalakrishnan, ARK | - |
dc.contributor.author | Kishore, U | - |
dc.contributor.author | Madan, T | - |
dc.date.accessioned | 2016-09-29T10:23:55Z | - |
dc.date.available | 2016-09-29T10:23:55Z | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | Regenerative Medicine, (2016) | en_US |
dc.identifier.issn | 1746-076X | - |
dc.identifier.uri | http://www.futuremedicine.com/loi/rme | - |
dc.identifier.uri | http://bura.brunel.ac.uk/handle/2438/13245 | - |
dc.description.abstract | Endometriosis is a leading, benign gynaecological disorder around the world. Last few years have witnessed tremendous growth in the field of endometriosis and endometrial stem cell (EnSC) research. Despite advancements in the biology and pathology of endometriosis, disease recurrence is still an enigma. Gene therapy holds promise in treating many pathologic conditions including endometriosis. Mesenchymal stem cells (MSCs) serve as ideal candidates for regenerative medicine and cell based therapies. Owing to their specificity to the endometrium, residing endometrial MSC populations could be utilized as ideal candidates for targeting endometrial disorders. Recently, we demonstrated their flexibility for gene transduction using adenoviral vectors. The review highlights the potential of endometrial MSCs in devising targeted gene therapies for endometriosis. | en_US |
dc.description.sponsorship | Post-doctoral fellowship program of the Indian Council for Medical Research, New Delhi, India | en_US |
dc.language.iso | en | en_US |
dc.publisher | Future Medicine | en_US |
dc.subject | Mesenchymal stem cells | en_US |
dc.subject | Gene therapy | en_US |
dc.subject | Endometriosis | en_US |
dc.subject | Angiogenesis | en_US |
dc.subject | Endometrial stem cells | en_US |
dc.title | Mesenchymal stem cells: a promising tool for targeted gene therapy of Endometriosis | en_US |
dc.type | Article | en_US |
dc.relation.isPartOf | Regenerative Medicine | - |
pubs.publication-status | Accepted | - |
Appears in Collections: | Dept of Life Sciences Embargoed Research Papers |
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FullText.pdf | 321.64 kB | Adobe PDF | View/Open |
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