Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/15158
Title: Early sensory processing in right hemispheric stroke patients with and without extinction
Authors: de Haan, B
Stoll, T
Karnath, H-O
Keywords: Science & Technology;Social Sciences;Life Sciences & Biomedicine;Behavioral Sciences;Neurosciences;Psychology, Experimental;Neurosciences & Neurology;Psychology;Extinction;Spatial attention;Subliminal perception;Right hemisphere;Stroke;VISUAL-ATTENTION;SPATIAL NEGLECT;ELECTROPHYSIOLOGICAL EVIDENCE;SELECTIVE ATTENTION;UNILATERAL NEGLECT;TACTILE EXTINCTION;PERCEPTUAL LOAD;LESIONS;BRAIN;RESPONSES
Issue Date: 2015
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
Citation: NEUROPSYCHOLOGIA, 2015, 73 pp. 141 - 150 (10)
Abstract: While extinction is most commonly viewed as an attentional disorder and not as a consequence of a failure to process contralesional sensory information, it has been speculated that early sensory processing of contralesional targets in extinction patients might not be fully normal. We used a masked visuo-motor response priming paradigm to study the influence of both contralesional and ipsilesional peripheral subliminal prime stimuli on central target performance, allowing us to compare the strength of the early sensory processing associated with these prime stimuli between right brain damaged patients with and without extinction as well as healthy elderly subjects. We found that the effect of an informative subliminal prime in the left contralesional visual field on central target performance was significantly reduced in both right brain damaged patients with and without extinction. The results suggest that a low-level early sensory deterioration of the neural representation for contralesional prime stimuli is a general consequence of right hemispheric brain damage unrelated to the presence or absence of extinction. This suggests that the presence of a spatial bias against contralesional information is not sufficient to elicit extinction. For extinction to occur, this spatial bias might need to be accompanied by a pathological (non-directional) reduction of attentional capacity.
URI: http://bura.brunel.ac.uk/handle/2438/15158
DOI: http://dx.doi.org/10.1016/j.neuropsychologia.2015.05.011
ISSN: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000357440200013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=f12c8c83318cf2733e615e54d9ed7ad5
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000357440200013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=f12c8c83318cf2733e615e54d9ed7ad5
0028-3932
1873-3514
Appears in Collections:Dept of Clinical Sciences Research Papers

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