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http://bura.brunel.ac.uk/handle/2438/23904
Title: | A Biomicrofluidic Screening Platform for Dysfunctional Endothelium-Targeted Nanoparticles and Therapeutics |
Authors: | Bazban-Shotorbani, S Gavins, F Kant, K Dufva, M Kamaly, N |
Issue Date: | 5-Jan-2022 |
Publisher: | Wiley-VCH GmbH |
Citation: | Bazban-Shotorbani, S., Gavins, F., Kant, K., Dufva, M. and Kamaly, N. (2022) 'A Biomicrofluidic Screening Platform for Dysfunctional Endothelium-Targeted Nanoparticles and Therapeutics', Advanced NanoBiomed Research, 2, 2270011, pp. 1-1 [cover picture]. doi: 10.1002/anbr.202270011. |
Abstract: | Copyright © 2022 The Author(s) and Wiley-VCH GmbH. Biomicrofluidic Models Biomicrofluidic models allow nanoparticle-cellular interactions to be studied under physiological flow conditions. Investigating nanoparticle biophysicochemical properties in models that resemble disease can provide valuable information about the nano-bio interface. By screening nanoparticles dynamically against a developed dysfunctional-endothelium-on chip model, Nazila Kamaly and co-workers show in article number 2100092 that nanoparticle size is a dominant factor beyond targeting ligands. Furthermore, tight junction disruption can be restored by the inflammation resolving mediator Annexin A1. |
URI: | https://bura.brunel.ac.uk/handle/2438/23904 |
DOI: | https://doi.org/10.1002/anbr.202270011 |
Other Identifiers: | 202270011 |
Appears in Collections: | Dept of Life Sciences Research Papers |
Files in This Item:
File | Description | Size | Format | |
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Cover-Picturel.pdf | 26.97 MB | Adobe PDF | View/Open |
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