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http://bura.brunel.ac.uk/handle/2438/24149
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DC Field | Value | Language |
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dc.contributor.author | Triay, R | - |
dc.contributor.author | Buchhanolla, P | - |
dc.contributor.author | Gaudet, A | - |
dc.contributor.author | Winter, V | - |
dc.contributor.author | Gaudet, A | - |
dc.contributor.author | Riel-Romero, RMS | - |
dc.contributor.author | Javalkar, V | - |
dc.contributor.author | Kelley, RE | - |
dc.contributor.author | Ansari, J | - |
dc.contributor.author | Faraji, M | - |
dc.contributor.author | Gonzalez-Toledo, E | - |
dc.contributor.author | Cuellar-Saenz, HH | - |
dc.contributor.author | Bailey, S | - |
dc.contributor.author | Siddaiah, H | - |
dc.contributor.author | Gavins, FNE | - |
dc.date.accessioned | 2022-02-19T13:54:03Z | - |
dc.date.available | 2022-02-19T13:54:03Z | - |
dc.date.issued | 2022-02-13 | - |
dc.identifier | 435 | - |
dc.identifier.citation | Triay, R., Buchhanolla, P., Gaudet, A., Winter, V., Gaudet, A., Riel-Romero, R.M.S., Javalkar, V., Kelley, R.E., Ansari, J., Faraji, M., Gonzalez-Toledo, E., Cuellar-Saenz, H.H., Bailey, S., Siddaiah, H. and Gavins, F.N.E. (2022) ‘The Spectrum of Acute Cerebrovascular Disease in Patients with COVID-19’, Biomedicines, 10 (2), 435, pp. 1-12. doi: 10.3390/biomedicines10020435. | en_US |
dc.identifier.uri | https://bura.brunel.ac.uk/handle/2438/24149 | - |
dc.description.abstract | Copyright: © 2022 by the authors. (1) Background: COVID-19 infection is responsible for the ongoing pandemic and acute cerebrovascular disease (CVD) has been observed in COVID-19 patients. (2) Methods: We conducted a retrospective, observational study of hospitalized adult patients admitted to our hospital with SARS-CoV-2 and acute cerebrovascular disease. All clinical data were reviewed including epidemiology, clinical features, laboratory data, neuroradiological findings, hospital management and course from 32 patients hospitalized for COVID-19 management with acute cerebrovascular disease. (3) Results: Acute CVD with COVID-19 was associated with higher NIH stroke scale on discharge compared to non-COVID-19 CVDs. Seizures complicated the hospital course in 16% of COVID-19 patients with CVD. The majority of the acute CVDs were ischemic (81%) in nature followed by hemorrhagic (22%). Acute CVD with COVID-19 resulted in average hospital stays greater than twice that of the control group (13 days in COVID-19, 5 days in control). Acute CVD with COVID-19 patients had worse clinical outcomes with 31% patient deaths and 6% discharged to hospice. In the control group, 6% of patients died. (4) Conclusions: Acute CVD associated with COVID-19 tends to be more complicated with unique and adverse clinical phenotype, longer hospital admissions, and worse clinical outcomes. | en_US |
dc.description.sponsorship | Royal Society Wolfson Fellowship | - |
dc.format.extent | 1 - 12 | - |
dc.format.medium | Electronic | - |
dc.language | en | - |
dc.language.iso | en_US | en_US |
dc.publisher | MDPI AG | en_US |
dc.rights | Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This is an open access article distributed under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.subject | COVID-19 | en_US |
dc.subject | cerebrovascular disease | en_US |
dc.subject | acute ischemic stroke | en_US |
dc.subject | seizures | en_US |
dc.subject | stroke | en_US |
dc.title | The Spectrum of Acute Cerebrovascular Disease in Patients with COVID-19 | en_US |
dc.type | Article | en_US |
dc.identifier.doi | https://doi.org/10.3390/biomedicines10020435 | - |
dc.relation.isPartOf | Biomedicines | - |
pubs.issue | 2 | - |
pubs.publication-status | Published online | - |
pubs.volume | 10 | - |
dc.identifier.eissn | 2227-9059 | - |
Appears in Collections: | Dept of Life Sciences Research Papers |
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