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DC Field | Value | Language |
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dc.contributor.author | Rao, R | - |
dc.contributor.author | Creese, B | - |
dc.contributor.author | Aarsland, D | - |
dc.contributor.author | Kalafatis, C | - |
dc.contributor.author | Khan, Z | - |
dc.contributor.author | Corbett, A | - |
dc.contributor.author | Ballard, C | - |
dc.date.accessioned | 2023-11-17T12:07:08Z | - |
dc.date.available | 2023-11-17T12:07:08Z | - |
dc.date.issued | 2021-11-12 | - |
dc.identifier | ORCID iD: Rahul Rao https://orcid.org/0000-0002-0262-5122 | - |
dc.identifier | ORCID iD: Byron Creese https://orcid.org/0000-0001-6490-6037 | - |
dc.identifier | ORCID iD: Anne Corbett https://orcid.org/0000-0003-2015-0316 | - |
dc.identifier | ORCID iD: Clive Ballard https://orcid.org/0000-0003-0022-5632 | - |
dc.identifier.citation | Rao, R. et al. (2022) 'Risky drinking and cognitive impairment in community residents aged 50 and over', Aging and Mental Health, 26 (12), pp. 2432 - 2439. doi: 10.1080/13607863.2021.2000938. | en_US |
dc.identifier.issn | 1360-7863 | - |
dc.identifier.uri | https://bura.brunel.ac.uk/handle/2438/27660 | - |
dc.description.abstract | Copyright © 2022 The Author(s). Objectives: Alcohol misuse is known to be a risk factor for dementia. This study aimed to explore the association between risky drinking and cognitive impairment in a cohort study of middle aged and older people at risk of dementia. Method: The sample comprised 15,582 people aged 50 and over drawn from the PROTECT study. Risky drinking was defined according to a score of 4 or above on the Alcohol Use Disorders Identification Test (AUDIT). Cognitive function was assessed on visual episodic memory, spatial working memory, verbal working memory and verbal reasoning. Results: Risky drinkers at baseline were more likely to be younger, male, white British, married, of higher educational status, current or past tobacco smokers and to have moderate to severe depression than non-risky drinkers. Risky drinkers were also more likely to be impaired on self-reported instrumental activities of daily living and subjective cognitive decline. At baseline, risky drinkers were less likely than non-risky drinkers to show impairment on verbal reasoning and spatial working memory but not on visual episodic memory or verbal working memory. Risky drinking at baseline predicted decline in cognitive function on visual episodic memory, verbal reasoning and spatial working memory at 2 year follow-up, but only verbal working memory and spatial working memory remained significant outcomes after controlling for possible confounders. Conclusion: Although of small effect size, the association between risky drinking and impairment on measures of working memory and visuospatial function warrants further examination; particularly given the possibility of partial reversibility in alcohol related cognitive impairment. | en_US |
dc.description.sponsorship | This paper represents independent research funded by the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King’s College London. | en_US |
dc.format.extent | 2432 - 2439 | - |
dc.format.medium | Print-Electronic | - |
dc.language | English | - |
dc.language.iso | en | en_US |
dc.publisher | Routledge (Taylor & Francis Group) | en_US |
dc.rights | Copyright © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | - |
dc.subject | alcohol | en_US |
dc.subject | older adults | en_US |
dc.subject | dementia | en_US |
dc.subject | cognitive function | en_US |
dc.title | Risky drinking and cognitive impairment in community residents aged 50 and over | en_US |
dc.type | Article | en_US |
dc.identifier.doi | https://doi.org/10.1080/13607863.2021.2000938 | - |
dc.relation.isPartOf | Aging and Mental Health | - |
pubs.issue | 12 | - |
pubs.publication-status | Published | - |
pubs.volume | 26 | - |
dc.identifier.eissn | 1364-6915 | - |
dc.rights.holder | The Author(s) | - |
Appears in Collections: | Dept of Life Sciences Research Papers |
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FullText.pdf | Copyright © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. | 1.07 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License