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DC Field | Value | Language |
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dc.contributor.author | Raywood, E | - |
dc.contributor.author | Shannon, H | - |
dc.contributor.author | Filipow, N | - |
dc.contributor.author | Tanriver, G | - |
dc.contributor.author | Stanojevic, S | - |
dc.contributor.author | Kapoor, K | - |
dc.contributor.author | Douglas, H | - |
dc.contributor.author | O'Connor, R | - |
dc.contributor.author | Murray, N | - |
dc.contributor.author | Black, B | - |
dc.contributor.author | Main, E | - |
dc.date.accessioned | 2024-03-24T15:12:20Z | - |
dc.date.available | 2024-03-24T15:12:20Z | - |
dc.date.issued | 2022-10-07 | - |
dc.identifier | ORCiD: Emma Raywood https://orcid.org/0000-0002-0993-5115 | - |
dc.identifier | ORCiD: Harriet Shannon https://orcid.org/0000-0003-2190-7245 | - |
dc.identifier | ORCiD: Gizem Tanriver https://orcid.org/0000-0002-0195-5672 | - |
dc.identifier | ORCiD: Sanja Stanojevic https://orcid.org/0000-0001-7931-8051 | - |
dc.identifier | ORCiD: Helen Douglas https://orcid.org/0000-0002-5184-6300 | - |
dc.identifier | ORCiD: Eleanor Main https://orcid.org/0000-0002-9739-3167 | - |
dc.identifier.citation | Raywood, E. et al. (2023) 'Quantity and quality of airway clearance in children and young people with cystic fibrosis', Journal of Cystic Fibrosis, 22 (2), pp. 344 - 351. doi: 10.1016/j.jcf.2022.09.008. | en_US |
dc.identifier.issn | 1569-1993 | - |
dc.identifier.uri | https://bura.brunel.ac.uk/handle/2438/28625 | - |
dc.description | Supplementary materials are online at: https://www.sciencedirect.com/science/article/pii/S1569199322006865#sec0016 . | en_US |
dc.description.abstract | Children and young people with CF (CYPwCF) get advice about using positive expiratory pressure (PEP) or oscillating PEP (OPEP) devices to clear sticky mucus from their lungs. However, little is known about the quantity (number of treatments, breaths, or sets) or quality (breath pressures and lengths) of these daily airway clearance techniques (ACTs) undertaken at home. This study used electronic pressure sensors to record real time breath-by-breath data from 145 CYPwCF (6–16y) during routine ACTs over 2 months. ACT quantity and quality were benchmarked against individual prescriptions and accepted recommendations for device use. In total 742,084 breaths from 9,081 treatments were recorded. Individual CYPwCF maintained consistent patterns of ACT quantity and quality over time. Overall, 60% of CYPwCF did at least half their prescribed treatments, while 27% did fewer than a quarter. About 77% of pre-teens did the right number of daily treatments compared with only 56% of teenagers. CYPwCF usually did the right number of breaths. ACT quality (recommended breath length and pressure) varied between participants and depended on device. Breath pressures, lengths and pressure-length relationships were significantly different between ACT devices. PEP devices encouraged longer breaths with lower pressures, while OPEP devices encouraged shorter breaths with higher pressures. More breaths per treatment were within advised ranges for both pressure and length using PEP (30–31%) than OPEP devices (1–3%). Objective measures of quantity and quality may help to optimise ACT device selection and support CYPwCF to do regular effective ACTs. | en_US |
dc.description.sponsorship | Project Fizzyo was supported by the UCL Rosetrees Stoneygate prize (M712), a Cystic Fibrosis Trust Clinical Excellence and Innovation Award (CEA010), A UCL Partners award and the HEFCE Higher Education Innovation Fund (KEI2017–01–04). HD was funded by the CF Trust Youth Activity Unlimited SRC and an NIHR GOSH BRC internship. All work at UCL GOSICH is supported by the NIHR GOSH BRC. | en_US |
dc.format.extent | 344 - 351 | - |
dc.language | English | - |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | Copyright © 2022 The Authors. Published by Elsevier B.V. on behalf of European Cystic Fibrosis Society. This is an open access article under the CC BY-NC-ND license ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | - |
dc.subject | airway clearance techniques | en_US |
dc.subject | chest physiotherapy | en_US |
dc.subject | paediatric | en_US |
dc.subject | physiotherapy | en_US |
dc.subject | respiratory | en_US |
dc.title | Quantity and quality of airway clearance in children and young people with cystic fibrosis | en_US |
dc.type | Article | en_US |
dc.identifier.doi | https://doi.org/10.1016/j.jcf.2022.09.008 | - |
dc.relation.isPartOf | Journal of Cystic Fibrosis | - |
pubs.issue | 2 | - |
pubs.publication-status | Published | - |
pubs.volume | 22 | - |
dc.identifier.eissn | 1873-5010 | - |
dc.rights.license | https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.en | - |
dc.rights.holder | The Authors | - |
Appears in Collections: | Dept of Health Sciences Research Papers |
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FullText.pdf | Copyright © 2022 The Authors. Published by Elsevier B.V. on behalf of European Cystic Fibrosis Society. This is an open access article under the CC BY-NC-ND license ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) | 862.02 kB | Adobe PDF | View/Open |
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