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DC Field | Value | Language |
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dc.contributor.author | Woodbridge, HR | - |
dc.contributor.author | McCarthy, CJ | - |
dc.contributor.author | Jones, M | - |
dc.contributor.author | Willis, M | - |
dc.contributor.author | Antcliffe, DB | - |
dc.contributor.author | Alexander, CM | - |
dc.contributor.author | Gordon, AC | - |
dc.date.accessioned | 2024-06-05T10:22:36Z | - |
dc.date.available | 2024-06-05T10:22:36Z | - |
dc.date.issued | 2024-04-30 | - |
dc.identifier | ORCiD: Mandy Jones https://orcid.org/0000-0002-3588-9060 | - |
dc.identifier | 144 | - |
dc.identifier.citation | Woodbridge, H.R. et al. (2024) 'Assessing the safety of physical rehabilitation in critically ill patients: a Delphi study', Critical Care, 28 (1), 144, pp. 1 - 15. doi: 10.1186/s13054-024-04919-x. | en_US |
dc.identifier.issn | 1364-8535 | - |
dc.identifier.uri | https://bura.brunel.ac.uk/handle/2438/29124 | - |
dc.description | Availability of data and materials: All grouped data is provided in the supplementary tables. Individual responses and data cannot be made publicly available due to participant confidentiality requirements. | en_US |
dc.description.abstract | Background: Physical rehabilitation of critically ill patients is implemented to improve physical outcomes from an intensive care stay. However, before rehabilitation is implemented, a risk assessment is essential, based on robust safety data. To develop this information, a uniform definition of relevant adverse events is required. The assessment of cardiovascular stability is particularly relevant before physical activity as there is uncertainty over when it is safe to start rehabilitation with patients receiving vasoactive drugs. Methods: A three-stage Delphi study was carried out to (a) define adverse events for a general ICU cohort, and (b) to define which risks should be assessed before physical rehabilitation of patients receiving vasoactive drugs. An international group of intensive care clinicians and clinician researchers took part. Former ICU patients and their family members/carers were involved in generating consensus for the definition of adverse events. Round one was an open round where participants gave their suggestions of what to include. In round two, participants rated their agreements with these suggestions using a five-point Likert scale; a 70% consensus agreement threshold was used. Round three was used to re-rate suggestions that had not reached consensus, whilst viewing anonymous feedback of participant ratings from round two. Results: Twenty-four multi-professional ICU clinicians and clinician researchers from 10 countries across five continents were recruited. Average duration of ICU experience was 18 years (standard deviation 8) and 61% had publications related to ICU rehabilitation. For the adverse event definition, five former ICU patients and one patient relative were recruited. The Delphi process had a 97% response rate. Firstly, 54 adverse events reached consensus; an adverse event tool was created and informed by these events. Secondly, 50 risk factors requiring assessment before physical rehabilitation of patients receiving vasoactive drugs reached consensus. A second tool was created, informed by these suggestions. Conclusions: The adverse event tool can be used in studies of physical rehabilitation to ensure uniform measurement of safety. The risk assessment tool can be used to inform clinical practise when risk assessing when to start rehabilitation with patients receiving vasoactive drugs. Trial registration: This study protocol was retrospectively registered on https://www.researchregistry.com/ (researchregistry2991). | en_US |
dc.description.sponsorship | This report is independent research arising from a Clinical Doctoral Research Fellowship, awarded to HRW, (ICA-CDRF-2015-01-026), supported by the National Institute for Health Research (NIHR) and Health Education England. We acknowledge the support of the NIHR Clinical Research Network and infrastructure support for this research was provided by the NIHR Imperial Biomedical Research Centre (BRC). HRW, MW, DBA, CMA, ACG are supported by the NIHR Imperial BRC and ACG by an NIHR Research Professorship (RP-2015-06-018). DBA is funded by the NIHR. | en_US |
dc.format.extent | 1 - 15 | - |
dc.language | English | - |
dc.language.iso | en | en_US |
dc.publisher | BMC (part of Springer Nature) | en_US |
dc.rights | Copyright © The Author(s) 2024. Rights and permissions: Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.subject | mobilisation | en_US |
dc.subject | adverse events | en_US |
dc.subject | vasoactive drugs | en_US |
dc.subject | intensive care unit | en_US |
dc.title | Assessing the safety of physical rehabilitation in critically ill patients: a Delphi study | en_US |
dc.type | Article | en_US |
dc.date.dateAccepted | 2024-04-17 | - |
dc.identifier.doi | https://doi.org/10.1186/s13054-024-04919-x | - |
dc.relation.isPartOf | Critical Care | - |
pubs.issue | 1 | - |
pubs.publication-status | Published online | - |
pubs.volume | 28 | - |
dc.identifier.eissn | 1466-609X | - |
dc.rights.license | https://creativecommons.org/licenses/by/4.0/legalcode.en | - |
dc.rights.holder | The Author(s) | - |
Appears in Collections: | Dept of Health Sciences Research Papers |
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