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DC Field | Value | Language |
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dc.contributor.author | Aloj, L | - |
dc.contributor.author | Attili, B | - |
dc.contributor.author | Lau, D | - |
dc.contributor.author | Caraco, C | - |
dc.contributor.author | Lechermann, LM | - |
dc.contributor.author | Mendichovszky, IA | - |
dc.contributor.author | Harper, I | - |
dc.contributor.author | Cheow, H | - |
dc.contributor.author | Casey, RT | - |
dc.contributor.author | Sala, E | - |
dc.contributor.author | Gilbert, FJ | - |
dc.contributor.author | Gallagher, FA | - |
dc.date.accessioned | 2024-07-26T07:22:51Z | - |
dc.date.available | 2024-07-26T07:22:51Z | - |
dc.date.issued | 2020-06-12 | - |
dc.identifier | ORCiD: Luigi Aloj https://orcid.org/0000-0002-7452-4961 | - |
dc.identifier | ORCiD: Ai Hui Doreen Lau https://orcid.org/0000-0002-7623-2401 | - |
dc.identifier | ORCiD: Laura Lechermann https://orcid.org/0000-0002-2742-6269 | - |
dc.identifier | ORCiD: Evis Sala https://orcid.org/0000-0002-5518-9360 | - |
dc.identifier | ORCiD: Fiona Gilbert https://orcid.org/0000-0002-0124-9962 | - |
dc.identifier | ORCiD: Ferdia Gallagher https://orcid.org/0000-0003-4784-5230 | - |
dc.identifier.citation | Aloj, L. et al. (2021) 'The emerging role of cell surface receptor and protein binding radiopharmaceuticals in cancer diagnostics and therapy', Nuclear Medicine and Biology, 92, pp. 53 - 64. doi: 10.1016/j.nucmedbio.2020.06.005. | en_US |
dc.identifier.issn | 0969-8051 | - |
dc.identifier.uri | https://bura.brunel.ac.uk/handle/2438/29417 | - |
dc.description.abstract | Targeting specific cell membrane markers for both diagnostic imaging and radionuclide therapy is a rapidly evolving field in cancer research. Some of these applications have now found a role in routine clinical practice and have been shown to have a significant impact on patient management. Several molecular targets are being investigated in ongoing clinical trials and show promise for future implementation. Advancements in molecular biology have facilitated the identification of new cancer-specific targets for radiopharmaceutical development. | en_US |
dc.description.sponsorship | This work was supported by Cancer Research UK, the CRUK Cambridge Centre, the CRUK & Engineering and Physical Science Research Council (EPSRC) Cancer Imaging Centre in Cambridge and Manchester, the Mark Foundation for Cancer Research, Addenbrooke's Charitable Trust, the National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre, Cambridge Experimental Cancer Medicine Centre, CRUK National Cancer Imaging Translational Accelerator (NCITA). | en_US |
dc.format.extent | 53 - 64 | - |
dc.format.medium | Print-Electronic | - |
dc.language | English | - |
dc.language.iso | en_US | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | Copyright © 2020 Elsevier. All rights reserved. This manuscript version is made available under the Creative Commons (CC-BY-NC-ND 4.0) Attribution-NonCommercial-NoDerivatives 4.0 International license (https://creativecommons.org/licenses/by-nc-nd/4.0/), see: https://www.elsevier.com/about/policies/sharing. | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | - |
dc.subject | receptors | en_US |
dc.subject | cell membrane proteins | en_US |
dc.subject | positron emission tomography | en_US |
dc.subject | targeted radionuclide therapy | en_US |
dc.subject | radiopharmaceutical development | en_US |
dc.title | The emerging role of cell surface receptor and protein binding radiopharmaceuticals in cancer diagnostics and therapy | en_US |
dc.type | Article | en_US |
dc.date.dateAccepted | 2020-06-10 | - |
dc.identifier.doi | https://doi.org/10.1016/j.nucmedbio.2020.06.005 | - |
dc.relation.isPartOf | Nuclear Medicine and Biology | - |
pubs.publication-status | Published | - |
pubs.volume | 92 | - |
dc.identifier.eissn | 1872-9614 | - |
dc.rights.holder | Elsevier | - |
Appears in Collections: | Dept of Life Sciences Research Papers |
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FullText.pdf | Copyright © 2020 Elsevier. All rights reserved. This manuscript version is made available under the Creative Commons (CC-BY-NC-ND 4.0) Attribution-NonCommercial-NoDerivatives 4.0 International license (https://creativecommons.org/licenses/by-nc-nd/4.0/), see: https://www.elsevier.com/about/policies/sharing. | 768.21 kB | Adobe PDF | View/Open |
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