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http://bura.brunel.ac.uk/handle/2438/30779Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Manca, R | - |
| dc.contributor.author | Flatt, JD | - |
| dc.contributor.author | Venneri, A | - |
| dc.date.accessioned | 2025-02-21T09:23:40Z | - |
| dc.date.available | 2025-02-21T09:23:40Z | - |
| dc.date.issued | 2025-01-18 | - |
| dc.identifier | ORCiD: Riccardo Manca https://orcid.org/0000-0003-1715-6442 | - |
| dc.identifier | ORCiD: Jason D. Flatt https://orcid.org/0000-0003-1244-738X | - |
| dc.identifier | ORCiD: Annalena Venneri https://orcid.org/0000-0002-9488-2301 | - |
| dc.identifier | Article number 90 | - |
| dc.identifier.citation | Manca, R., Flatt, J.D. and Venneri, A. (2025) 'Differential Impact of Risk Factors for Cognitive Decline in Heterosexual and Sexual Minority Older Adults in England', Brain Sciences, 15 (1), 90, pp. 1 - 18. doi: 10.3390/brainsci15010090. | en_US |
| dc.identifier.uri | https://bura.brunel.ac.uk/handle/2438/30779 | - |
| dc.description | Data Availability Statement: The data used in the study were obtained from the UK Data Service archive upon registration and can be found on the UK Data Service repository (https://ukdataservice.ac.uk/). | en_US |
| dc.description.abstract | Background/Objectives: Sexual minority older adults (SMOAs) report greater subjective cognitive decline (SCD) than heterosexual older adults (HOAs). This study aimed to compare the impact of multiple psycho-social risk factors on objective and subjective cognitive decline in HOAs and SMOAs. Methods: Two samples of self-identified HOAs and SMOAs were selected from the English Longitudinal Study of Ageing. Reliable change indices for episodic and semantic memory were created to assess cognitive decline. SCD was self-reported for memory and general cognition. Depressive symptoms, loneliness, marital status and socio-economic status were investigated as risk factors. Results: No between-group differences were found in cognitive decline. Higher depression was associated with greater SCD risk and worse semantic memory decline. The latter effect was stronger in SMOAs. The findings were largely replicated in the sensitivity analysis. Conclusions: Poor mental health may represent the strongest driver of cognitive decline in SMOAs and to a greater extent than in HOAs. | en_US |
| dc.description.sponsorship | This work was supported by an Alzheimer’s Association Grant (AARF-22-919481) to RM. JF is supported by the National Institutes on Aging, the National Institutes of Health (R01AG083177, K01AG056669 and R24AG066599), the Alzheimer’s Association (AARGD-22-929144) and the Michael J. Fox Foundation for Parkinson’s Research (MJFF-020943). AV is supported by funding obtained under the National Recovery and Resilience Plan (NRRP), Mission 4 Component 2 Investment 1.3—Call for tender No. 341 of 15/03/2022 of the Italian Ministry of University and Research funded by the European Union—NextGenerationEU (project code PE0000006), Concession Decree No. 1553 of 11/10/2022 adopted by the Italian Ministry of University and Research and CUP D93C22000930002 “A multiscale integrated approach to the study of the nervous system in health and disease” (MNESYS). | en_US |
| dc.format.extent | 1 - 18 | - |
| dc.format.medium | Electronic | - |
| dc.language | English | - |
| dc.language.iso | en_US | en_US |
| dc.publisher | MDPI | en_US |
| dc.rights | Attribution 4.0 International | - |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
| dc.subject | cognitive decline | en_US |
| dc.subject | memory | en_US |
| dc.subject | sexual orientation | en_US |
| dc.subject | minority | en_US |
| dc.subject | mental health | en_US |
| dc.subject | marital status | en_US |
| dc.subject | loneliness | en_US |
| dc.subject | socio-economic status | en_US |
| dc.title | Differential Impact of Risk Factors for Cognitive Decline in Heterosexual and Sexual Minority Older Adults in England | en_US |
| dc.type | Article | en_US |
| dc.date.dateAccepted | 2025-01-14 | - |
| dc.identifier.doi | https://doi.org/10.3390/brainsci15010090 | - |
| dc.relation.isPartOf | Brain Sciences | - |
| pubs.issue | 1 | - |
| pubs.publication-status | Published | - |
| pubs.volume | 15 | - |
| dc.identifier.eissn | 2076-3425 | - |
| dc.rights.license | https://creativecommons.org/licenses/by/4.0/legalcode.en | - |
| dcterms.dateAccepted | 2025-01-14 | - |
| dc.rights.holder | The authors | - |
| Appears in Collections: | Dept of Life Sciences Research Papers | |
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|---|---|---|---|---|
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