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Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/31217
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dc.contributor.authorLea-Smith, DJ-
dc.contributor.authorHassard, F-
dc.contributor.authorCoulon, F-
dc.contributor.authorPartridge, N-
dc.contributor.authorHorsfall, L-
dc.contributor.authorParker, KDJ-
dc.contributor.authorSmith, RDJ-
dc.contributor.authorMcCarthy, RR-
dc.contributor.authorMcKew, B-
dc.contributor.authorGutierrez, T-
dc.contributor.authorKumar, V-
dc.contributor.authorDotro, G-
dc.contributor.authorYang, Z-
dc.contributor.authorCurtis, TP-
dc.contributor.authorGolyshin, P-
dc.contributor.authorHeaven, S-
dc.contributor.authorJefferson, B-
dc.contributor.authorJeffrey, P-
dc.contributor.authorJones, DL-
dc.contributor.authorLe Corre Pidou, K-
dc.contributor.authorLiu, Y-
dc.contributor.authorLyu, T-
dc.contributor.authorSmith, C-
dc.contributor.authorYakunin, A-
dc.contributor.authorZhang, Y-
dc.contributor.authorKrasnogor, N-
dc.contributor.otherEBIC partners-
dc.date.accessioned2025-05-12T15:12:05Z-
dc.date.available2025-05-12T15:12:05Z-
dc.date.issued2025-04-14-
dc.identifierORCiD: David J. Lea-Smith https://orcid.org/0000-0003-2463-406X-
dc.identifierORCiD: Francis Hassard https://orcid.org/0000-0003-4803-6523-
dc.identifierORCiD: Frederic Coulon https://orcid.org/0000-0002-4384-3222-
dc.identifierORCiD: Natalie Partridge https://orcid.org/0009-0005-0991-5455-
dc.identifierORCiD: Louise Horsfall https://orcid.org/0000-0003-1594-2992-
dc.identifierORCiD: Kyle D. J. Parker https://orcid.org/0009-0005-7174-4423-
dc.identifierORCiD: Robert D. J. Smith https://orcid.org/0000-0002-5814-6032-
dc.identifierORCiD: Ronan R. McCarthy https://orcid.org/0000-0002-7480-6352-
dc.identifierORCiD: Tony Gutierrez https://orcid.org/0000-0002-6127-8511-
dc.identifierORCID: Zhugen Yang https://orcid.org/0000-0003-4183-8160-
dc.identifierORCiD: Natalio Krasnogor https://orcid.org/0000-0002-2651-4320-
dc.identifierArticle number: 3538-
dc.identifier.citationLea-Smith, D.J. et al. for the EBIC partners (2025) 'Engineering biology applications for environmental solutions: potential and challenges', Nature Communications, 16 (1), 3538, pp. 1 - 12. doi: 10.1038/s41467-025-58492-0.-
dc.identifier.urihttps://bura.brunel.ac.uk/handle/2438/31217-
dc.descriptionSupplementary information is available online at: https://www.nature.com/articles/s41467-025-58492-0#Sec9 .-
dc.description.abstractEngineering biology applies synthetic biology to address global environmental challenges like bioremediation, biosequestration, pollutant monitoring, and resource recovery. This perspective outlines innovations in engineering biology, its integration with other technologies (e.g., nanotechnology, IoT, AI), and commercial ventures leveraging these advancements. We also discuss commercialisation and scaling challenges, biosafety and biosecurity considerations including biocontainment strategies, social and political dimensions, and governance issues that must be addressed for successful real-world implementation. Finally, we highlight future perspectives and propose strategies to overcome existing hurdles, aiming to accelerate the adoption of engineering biology for environmental solutions.-
dc.description.sponsorshipAll authors acknowledge support from the UK Research and Innovation (UKRI) Biological Sciences Research Council (BBSRC) grant BB/Y008332/1. D.J.L-S acknowledges support from UKRI BBSRC grant BB/S020365. F.C. and T.G. acknowledges support from UKRI BBSRC grant BB/S009795/1. ZY thanks The Leverhulme Trust Research Leadership Awards RL-2022-041. N.K. acknowledges support from UKRI BBSRC grant BB/Y007638/1, the Department for Science, Innovation and Technology (DSIT) and the Royal Academy of Engineering for his Chair in Emerging Technologies award.-
dc.format.extent1 - 12-
dc.format.mediumElectronic-
dc.languageEnglish-
dc.publisherSpringer Nature-
dc.rightsAttribution 4.0 International-
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/-
dc.subjectapplied microbiology-
dc.subjectbioremediation-
dc.subjectenvironmental biotechnology-
dc.subjectgovernance-
dc.subjectmolecular engineering-
dc.titleEngineering biology applications for environmental solutions: potential and challenges-
dc.typeJournal Article-
dc.date.dateAccepted2025-03-24-
dc.identifier.doihttps://doi.org/10.1038/s41467-025-58492-0-
dc.relation.isPartOfNature Communications-
pubs.issue1-
pubs.publication-statusPublished online-
pubs.volume16-
dc.identifier.eissn2041-1723-
dc.rights.licensehttps://creativecommons.org/licenses/by/4.0/legalcode.en-
dcterms.dateAccepted2025-03-24-
dc.rights.holderThe Author(s)-
Appears in Collections:Dept of Life Sciences Research Papers

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