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Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/31538
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dc.contributor.authorAnsari, J-
dc.contributor.authorVital, S-
dc.contributor.authorEsen, E-
dc.contributor.authorGavins, F-
dc.coverage.spatialOnline-
dc.date.accessioned2025-07-11T15:00:28Z-
dc.date.available2025-07-11T15:00:28Z-
dc.date.issued2020-12-13-
dc.identifierORCiD: Felicity N. E. Gavins https://orcid.org/0000-0001-7008-5423-
dc.identifierAbstract number: OC004-
dc.identifier.citationAnsari, J. et al. (2020) 'Targeting Peptidyl Arginine Deiminase 4 and NADPH Oxidase Pathways Regulates Neutrophil Dependent Thrombo-inflammation', British Journal of Pharmacology, 178 (2), Abstract number OC004, pp. 409 - 410 (2), pp. 409 - 410. doi: 10.1111/bph.15316.en_US
dc.identifier.issn0007-1188-
dc.identifier.urihttps://bura.brunel.ac.uk/handle/2438/31538-
dc.descriptionMeeting abstract presented at Pharmacology 2020, Online, 14-18 December, 2020: Session: Oral Communications - Cardiovascular & Respiratory Pharmacology 1.en_US
dc.description.abstractIntroduction/Background & aims: Excessive neutrophil extracellular trap (NET) production is associated with the pathogenesis of thrombo-inflammatory diseases e.g. sickle cell disease (SCD), and is catalyzed by the enzyme Peptidyl Arginine Deiminase-4 (PAD4). Neutrophil reactive oxygen species (ROS), especially NADPH-oxidase (NOX) interacts with PAD4 and is critical for its function. Here, we studied the critical role of neutrophilic NOX in NET formation associated with thrombo-inflammation. ...en_US
dc.format.extent409 - 410 (2)-
dc.format.mediumPrint-Electronic-
dc.languageEnglish-
dc.language.isoenen_US
dc.publisherWiley on behalf of The British Pharmacological Societyen_US
dc.rightsCopyright © 2020 The British Pharmacological Society. This is the peer reviewed version of the following article: 'Targeting Peptidyl Arginine Deiminase 4 and NADPH Oxidase Pathways Regulates Neutrophil Dependent Thrombo-inflammation', Selected Abstracts From Pharmacology 2020. Br J Pharmacol, 178: Abstract number OC004, pp. 409-410., which has been published in final form at https://doi.org/10.1111/bph.15316. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions (see: https://authorservices.wiley.com/author-resources/Journal-Authors/licensing/self-archiving.html).-
dc.rights.urihttps://authorservices.wiley.com/author-resources/Journal-Authors/licensing/self-archiving.html-
dc.sourcePharmacology 2020.-
dc.sourcePharmacology 2020.-
dc.titleTargeting Peptidyl Arginine Deiminase 4 and NADPH Oxidase Pathways Regulates Neutrophil Dependent Thrombo-inflammationen_US
dc.typeConference Paperen_US
dc.date.dateAccepted2020-10-16-
dc.identifier.doihttps://doi.org/10.1111/bph.15316-
dc.relation.isPartOfBritish Journal of Pharmacology-
pubs.finish-date2020-12-18-
pubs.finish-date2020-12-18-
pubs.issue2-
pubs.publication-statusPublished-
pubs.start-date2020-12-14-
pubs.start-date2020-12-14-
pubs.volume178-
dc.identifier.eissn1476-5381-
dcterms.dateAccepted2020-10-16-
dc.rights.holderThe British Pharmacological Society-
Appears in Collections:Dept of Life Sciences Research Papers

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