Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/32150
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dc.contributor.authorHenry, ML-
dc.contributor.authorO'Connell, NE-
dc.contributor.authorRiley, RD-
dc.contributor.authorMoons, KGM-
dc.contributor.authorShea, BJ-
dc.contributor.authorHooft, L-
dc.contributor.authorDamen, JAA-
dc.contributor.authorSkoetz, N-
dc.contributor.authorWallwork, SB-
dc.contributor.authorMoseley, LG-
dc.date.accessioned2025-10-14T15:17:46Z-
dc.date.available2025-10-14T15:17:46Z-
dc.date.issued2025-12-22-
dc.identifierORCiD: Michael L. Henry https://orcid.org/0000-0003-2871-6695-
dc.identifierORCiD: Neil O'Connell https://orcid.org/0000-0003-1989-4537-
dc.identifierORCiD: Richard D. Riley https://orcid.org/0000-0001-8699-0735-
dc.identifierORCiD: Karel G. M. Moons https://orcid.org/0000-0003-2118-004X-
dc.identifierORCiD: Lotty Hooft https://orcid.org/0000-0002-7950-2980-
dc.identifierORCiD: Johanna A. A. Damen https://orcid.org/0000-0001-7401-4593-
dc.identifierORCiD: Nicole Skoetz https://orcid.org/0000-0003-4744-6192-
dc.identifierArticle number: e085718-
dc.identifier.citationHenry, M.L. et al. (2025) 'AMSTAR-PF: a critical appraisal tool for systematic reviews of prognostic factor studies', BMJ: British Medical Journal, 391, e085718, pp. 1 - 11. doi: 10.1136/bmj-2025-085718.en_US
dc.identifier.issn1759-2151-
dc.identifier.urihttps://bura.brunel.ac.uk/handle/2438/32150-
dc.descriptionSummary Points: • Research into prognostic factors is vital for many areas of healthcare. • Confidence in the findings of systematic reviews of prognostic factor research can be compromised in a variety of ways. • AMSTAR-PF (A MeaSurement Tool to Assess systematic Reviews of Prognostic Factor studies), based on AMSTAR 2, has been developed, refined, and tested AMSTAR-PF uses signalling points and 19 questions over 14 domains to assist in coming to an overall judgment of confidence in the results of the review. • Providing a standardised and reliable tool to appraise review quality will assist users to ascertain confidence in the review’s findings.en_US
dc.descriptionData availability statement: Data related to agreement testing can be found in the referenced paper, or on reasonable request from the corresponding author at neil.oconnell@brunel.ac.uk. The draft versions of the tool and guidance notes generated during the development process are available on reasonable request, from the corresponding author.-
dc.descriptionA preprint version of the article is available at medRxiv, https://www.medrxiv.org/content/10.1101/2025.04.10.25325555v1 . It has not been certified by peer review. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice. The copyright holder for this preprint is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.-
dc.description.abstractThe ability to predict the onset or natural history of an illness, or how people may respond to a treatment, guides clinical decision making. These predictions are commonly based on prognostic factors: clinical, patient, or societal variables that are identified as being predictive of a certain future outcome. Prognostic factor research has increased across fields, with a subsequent increase in the number of systematic reviews of prognostic factors studies. Understanding the quality of such prognostic factor reviews is essential for confidence in their findings, but there is no quality appraisal instrument to specifically assess systematic reviews of prognostic factor studies. A MeaSurement Tool to Assess systematic Reviews of Prognostic Factor studies, AMSTAR-PF, has been developed to fill this gap.en_US
dc.description.sponsorshipThis work received no specific funding. MLH was supported by an Australian Government Research Training Scholarship. RDR was supported by funding from the MRC Better Methods Better Research panel (grant MR/V038168/1) and by the National Institute for Health and Care Research (NIHR) Birmingham Biomedical Research Centre at the University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham. GLM was supported by a leadership investigator grant from the National Health and Medical Research Council of Australia (ID 1178444). The funders had no role in considering the study design or in the collection, analysis, interpretation of data, writing of the report, or decision to submit the article for publication.en_US
dc.format.extent1 - 11-
dc.format.mediumPrint-Electronic-
dc.language.isoenen_US
dc.publisherBMJ Publishing Groupen_US
dc.relation.urihttps://www.medrxiv.org/content/10.1101/2025.04.10.25325555v1-
dc.rightsCreative Commons Attribution 4.0 International-
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/-
dc.titleAMSTAR-PF: a critical appraisal tool for systematic reviews of prognostic factor studiesen_US
dc.typeArticleen_US
dc.date.dateAccepted2025-10-13-
dc.identifier.doihttps://doi.org/10.1136/bmj-2025-085718-
dc.relation.isPartOfBMJ: British Medical Journal-
pubs.publication-statusPublished-
pubs.volume391-
dc.identifier.eissn0959-8138-
dc.rights.licensehttps://creativecommons.org/licenses/by/4.0/legalcode.en-
dcterms.dateAccepted2025-10-13-
dc.rights.holderAuthor(s) (or their employer(s))-
dc.contributor.orcidHenry, Michael L. [0000-0003-2871-6695]-
dc.contributor.orcidO'Connell, Neil [0000-0003-1989-4537]-
dc.contributor.orcidRiley, Richard D. [0000-0001-8699-0735]-
dc.contributor.orcidMoons, Karel G. M. [0000-0003-2118-004X]-
dc.contributor.orcidHooft, Lotty [0000-0002-7950-2980]-
dc.contributor.orcidDamen, Johanna A. A. [0000-0001-7401-4593]-
dc.contributor.orcidSkoetz, Nicole [0000-0003-4744-6192]-
Appears in Collections:Department of Health Sciences Research Papers

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