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http://bura.brunel.ac.uk/handle/2438/8156Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Pey, J | - |
| dc.contributor.author | Prada, J | - |
| dc.contributor.author | Beasley, JE | - |
| dc.contributor.author | Planes, FJ | - |
| dc.date.accessioned | 2014-03-18T12:10:42Z | - |
| dc.date.available | 2014-03-18T12:10:42Z | - |
| dc.date.issued | 2011 | - |
| dc.identifier.citation | Genome Biology, 12, Article R49, 2011 | en_US |
| dc.identifier.issn | 1474-760X | - |
| dc.identifier.uri | http://genomebiology.com/2011/12/5/R49 | en |
| dc.identifier.uri | http://bura.brunel.ac.uk/handle/2438/8156 | - |
| dc.description | Copyright © 2011 Pey et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | en_US |
| dc.description.abstract | Graph-based methods have been widely used for the analysis of biological networks. Their application to metabolic networks has been much discussed, in particular noting that an important weakness in such methods is that reaction stoichiometry is neglected. In this study, we show that reaction stoichiometry can be incorporated into path-finding approaches via mixed-integer linear programming. This major advance at the modeling level results in improved prediction of topological and functional properties in metabolic networks. | en_US |
| dc.description.sponsorship | Basque Government | en_US |
| dc.language | English | - |
| dc.language.iso | en | en_US |
| dc.publisher | Biomed Central Ltd | en_US |
| dc.subject | Metabolic networks | en_US |
| dc.subject | Computational biology | en_US |
| dc.subject | Algorithms | en_US |
| dc.subject | Pathways | en_US |
| dc.title | Path finding methods accounting for stoichiometry in metabolic networks | en_US |
| dc.type | Article | en_US |
| dc.identifier.doi | http://dx.doi.org/10.1186/gb-2011-12-5-r49 | - |
| pubs.organisational-data | /Brunel | - |
| pubs.organisational-data | /Brunel/Administration and Support Staff | - |
| pubs.organisational-data | /Brunel/Administration and Support Staff/Administration and Support Staff | - |
| pubs.organisational-data | /Brunel/Group Publication Pages | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/Brunel Business School - URCs and Groups | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/Brunel Business School - URCs and Groups/Centre for Research into Entrepreneurship, International Business and Innovation in Emerging Markets | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Arts - URCs and Groups | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Arts - URCs and Groups/Brunel Centre for Contemporary Writing | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Brunel Institute for Ageing Studies | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Brunel Institute of Cancer Genetics and Pharmacogenomics | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Centre for Systems and Synthetic Biology | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Information Systems, Computing and Mathematics - URCs and Groups | - |
| pubs.organisational-data | /Brunel/University Research Centres and Groups/School of Information Systems, Computing and Mathematics - URCs and Groups/Multidisclipary Assessment of Technology Centre for Healthcare (MATCH) | - |
| Appears in Collections: | Publications Dept of Mathematics Research Papers Mathematical Sciences | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Fulltext.pdf | 642.46 kB | Adobe PDF | View/Open |
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