Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/9926
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dc.contributor.authorBailey, DM-
dc.contributor.authorDavies, B-
dc.contributor.authorRomer, L-
dc.contributor.authorCastell, L-
dc.contributor.authorNewsholme, E-
dc.contributor.authorGandy, G-
dc.date.accessioned2015-01-23T16:12:26Z-
dc.date.available1998-
dc.date.available2015-01-23T16:12:26Z-
dc.date.issued1998-
dc.identifier.citationEuropean Journal of Applied Physiology, 78:4, pp. 360 - 368, 1998en_US
dc.identifier.issn0301-5548-
dc.identifier.urihttp://bura.brunel.ac.uk/handle/2438/9926-
dc.description.abstractElite distance runners participated in one of two studies designed to investigate the e ects of mod- erate altitude training (inspiratory partial pressure of oxygen »115±125 mmHg) on submaximal, maximal and supramaximal exercise performance following return to sea-level. Study 1 (New Mexico, USA) involved 14 subjects who were assigned to a 4-week altitude training camp (1500±2000 m) whilst 9 performance-matched subjects continued with an identical training programme at sea-level (CON). Ten EXP subjects who trained at 1640 m and 19 CON subjects also participated in study 2 (Krugersdorp, South Africa). Selected metabolic and cardiorespiratory parameters were determined with the subjects at rest and during exercise 21 days prior to (PRE) and 10 and 20 days following their return to sea- level (POST). Whole blood lactate decreased by 23% (P < 0.05 vs PRE) during submaximal exercise in the EXP group only after 20 days at sea-level (study 1). However, the lactate threshold and other measures of running economy remained unchanged. Similarly, su- pramaximal performance during a standardised track session did not change. Study 2 demonstrated that hypoxia per se did not alter performance. In contrast, in the EXP group supramaximal running velocity de- creased by 2% (P < 0.05) after 20 days at sea-level. Both studies were characterised by a 50% increase in the frequency of upper respiratory and gastrointestinal tract infections during the altitude sojourns, and two male subjects were diagnosed with infectious mononucleosis following their return to sea-level (study 1). Group mean plasma glutamine concentrations at rest decreased by 19% or 143 (74) lM (P < 0.001) after 3 weeks at alti- tude, which may have been implicated in the increased incidence of infectious illness.en_US
dc.format.extent360 - 368-
dc.format.extent360 - 368-
dc.language.isoenen_US
dc.subjectHypobaric hypoxiaen_US
dc.subjectInfectious mononucleosisen_US
dc.subjectPlasma glutamineen_US
dc.subjectImmunosuppressionen_US
dc.titleImplications of moderate altitude training for sea level endurance in elite distance runnersen_US
dc.typeArticleen_US
dc.relation.isPartOfEuropean Journal of Applied Physiology-
dc.relation.isPartOfEuropean Journal of Applied Physiology-
pubs.issue4-
pubs.issue4-
pubs.volume78-
pubs.volume78-
pubs.organisational-data/Brunel-
pubs.organisational-data/Brunel/Brunel Staff by College/Department/Division-
pubs.organisational-data/Brunel/Brunel Staff by College/Department/Division/College of Health and Life Sciences-
pubs.organisational-data/Brunel/Brunel Staff by College/Department/Division/College of Health and Life Sciences/Dept of Life Sciences-
pubs.organisational-data/Brunel/Brunel Staff by College/Department/Division/College of Health and Life Sciences/Dept of Life Sciences/Sport-
pubs.organisational-data/Brunel/University Research Centres and Groups-
pubs.organisational-data/Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups-
pubs.organisational-data/Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Brunel Institute for Ageing Studies-
pubs.organisational-data/Brunel/University Research Centres and Groups/School of Health Sciences and Social Care - URCs and Groups/Centre for Systems and Synthetic Biology-
Appears in Collections:Sport
Dept of Life Sciences Research Papers

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