Adaptive model of uncertainty in healthcare technology management See

Healthcare Technology Management (HTM) operates under significant uncertainty arising from technical, managerial, and macro-environmental factors. Existing risk assessment models—including recent data-driven and machine learning–based approaches—focus predominantly on internal maintenance variables and fail to ac...

Silenced by design: The collapse of gig worker voice under algorithmic control in an authoritarian labour market See

Digitalisation is reshaping the organisation of labour through algorithmic systems that govern work with minimal human involvement. While a growing literature examines these systems in Global North contexts, their operation within politically centralised and institutionally fragile environments remains ins...

Mild Behavioural Impairment and Everyday Functioning in Cognitively Unimpaired Older Adults: Evidence From the CAN-PROTECT Study See

Background: Recognizing early clinical signs of dementia is key to optimizing emerging therapies, including monoclonal antibodies. Mild behavioural impairment (MBI) characterizes later-life emergent and persistent nropsychiatric symptoms linked to greater dementia risk, representing a behavioural manifestatio...

Novel Methylation Markers in a Prostate Cancer Cohort are Associated with Disease Development and Relapse See

Prostate cancer remains one of the most common cancers among men globally. While significant strides have been made in diagnosis and treatment, understanding the complex genetic and epigenetic underpinnings of the disease remains crucial for guiding intervention and developing more personalized&#...

Good senior secondary vocational education: Educators’ experiences with subjectification and imagination’s heartwork at a Dutch college See

This study investigates how educators in Dutch senior secondary vocational education (SSVE) experience, conceptualise, enact ‘good education’. It addresses a gap in the existing research by offering the first application of Hogan’s ‘imagination’s heartwork’ to the Dutch SSVE context. Combining&#...

The Pan Prostate Cancer Group Dataset - Genomic, Transcriptomic and Methylation data for Clinical Discovery See

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Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant <i>Acinetobacter baumannii</i> Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials See

There is a critical need for novel therapeutic strategies to tackle multidrug‐resistant bacterial infections. Artificial sweeteners (AS) specifically acesulfame potassium, sodium saccharin, and sodium cyclamate, have recently demonstrated antimicrobial activity against multidrug‐resistant bacteria. In this study, po...

Risperidone prescription and use for people with dementia in care homes: a qualitative study exploring perceptions of residents, relatives and health and social care professionals See

Objectives: Risperidone is an antipsychotic used to treat behavioural symptoms of dementia such as agitation, which should be used as a last resort. However, it carries a number of severe side effects, including stroke. Prescribing data suggest regular use outside of this gu...

Validation of the care partner stress scale in the CAN-PROTECT study See

Background: Family and friend care partners play a vital role in supporting individuals with neurocognitive disorders, such as Alzheimer's disease dementia. Care partners are often uncompensated and face multifaceted challenges that contribute to stress. The Care Partner Stress Scale (...