Please use this identifier to cite or link to this item:
Title: Mesenchymal stem cells: a promising tool for targeted gene therapy of Endometriosis
Authors: Gopalakrishnan, ARK
Kishore, U
Madan, T
Keywords: Mesenchymal stem cells;Gene therapy;Endometriosis;Angiogenesis;Endometrial stem cells
Issue Date: 2016
Publisher: Future Medicine
Citation: Regenerative Medicine, (2016)
Abstract: Endometriosis is a leading, benign gynaecological disorder around the world. Last few years have witnessed tremendous growth in the field of endometriosis and endometrial stem cell (EnSC) research. Despite advancements in the biology and pathology of endometriosis, disease recurrence is still an enigma. Gene therapy holds promise in treating many pathologic conditions including endometriosis. Mesenchymal stem cells (MSCs) serve as ideal candidates for regenerative medicine and cell based therapies. Owing to their specificity to the endometrium, residing endometrial MSC populations could be utilized as ideal candidates for targeting endometrial disorders. Recently, we demonstrated their flexibility for gene transduction using adenoviral vectors. The review highlights the potential of endometrial MSCs in devising targeted gene therapies for endometriosis.
ISSN: 1746-076X
Appears in Collections:Dept of Life Sciences Embargoed Research Papers

Files in This Item:
File Description SizeFormat 
FullText.pdf321.64 kBAdobe PDFView/Open

Items in BURA are protected by copyright, with all rights reserved, unless otherwise indicated.